JLB2-110c
JLB2-110c activates MCRs receptor (mMC4R EC50 = 0.34 nM) and has a strong in vivo appetite suppressant effect.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3032608-72-0
- Fòrmula: C71H108N28O12
- Peso molecular:1545.80
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Chemical Information
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No. CAS 3032608-72-0
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Peso molecular 1545.80
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Fòrmula C71H108N28O12
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Sequence
Cyclo(Pro-His-{d-Phe}-Arg-Trp-{Dap}-{Lys(Ac-Arg-Arg-Arg)}-{d-Pro})
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Sequence Shortening
Cyclo(PH-{d-Phe}-RW-{Dap}-{Lys(Ac-RRR)}-{d-Pro})
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Ericson MD, et al. Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]. ACS Pharmacol Transl Sci. 2024 Apr 2;7(4):1114-1125. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)