KPC-2-IN-2
KPC-2-IN-2 (Compound 6c) is a potent Klebsiella pneumoniae carbapenemase (KPC-2) inhibitor (Ki=0.038 μM). KPC-2-IN-2 can enhance the activity of cefotaxime in KPC-2 expressing Escherichia coli.
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- No. CAS: 3034185-71-9
- Fòrmula: C12H10BN3O2S
- Peso molecular:271.10
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
IC50: 0.038 μM (KPC-2)[1]
KPC-2-IN-2 (5 and 50 μg/mL; 24 h) treatment shows excellent tolerance in HEK-293[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HEK-293
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Concentration:5 and 50 μg/ml
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Incubation Time:24 hours
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Result:Tolerated well in the presence or absence of 30 μg/ml cefotaxime (>80% viability after 24 h).
Chemical Information
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No. CAS 3034185-71-9
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Peso molecular 271.10
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Fòrmula C12H10BN3O2S
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SMILES
OB(C1=CC=CC(N2C=C(N=N2)C3=CSC=C3)=C1)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KPC-2-IN-2 Related Classifications
HY-150767 Related Classifications
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