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Referencia número: HY-126140

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MDRTB-IN-1

MDRTB-IN-1 (5aα) is an antibiotic which is against Mycobacterium tuberculosis H37Rv with a MIC₉₀ value of 10.5 μM.

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No. CAS: 1973401-05-6
Fòrmula: C₁₅H₁₈N₂O₃
Peso molecular:274.32

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

MDRTB-IN-1 Chemical Structure

No. CAS: 1973401-05-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

MDRTB-IN-1 (5aα) is an antibiotic which is against Mycobacterium tuberculosis H37Rv with a MIC₉₀ value of 10.5 μM^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
J774.A1	IC₅₀	196.4 μM Compound: 5a-alpha	Cytotoxicity against mouse J774A.1 cells after 24 hrs by resazurin dye-based fluorescence assay Cytotoxicity against mouse J774A.1 cells after 24 hrs by resazurin dye-based fluorescence assay	[PMID: 30803803]
MRC5	IC₅₀	>364.5 μM Compound: 5a-alpha	Cytotoxicity against human MRC5 cells after 24 hrs by resazurin dye-based fluorescence assay Cytotoxicity against human MRC5 cells after 24 hrs by resazurin dye-based fluorescence assay	[PMID: 30803803]

Chemical Information

No. CAS 1973401-05-6
Peso molecular 274.32
Fòrmula C₁₅H₁₈N₂O₃
SMILES

O=C(OCC)C1=C(C)OC2=NC(N3CCCC3)=CC=C21
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Fumagalli F, et al. Exploiting the furo[2,3-b]pyridine core against multidrug-resistant Mycobacterium tuberculosis. Bioorg Med Chem Lett. 2019 Apr 15; 29(8):974-977. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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