SB-436811
SB-436811 is a human urotensin-II receptor antagonist with a pKi value of 6.7.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 346729-66-6
- Fòrmula: C23H29Cl2N3O2
- Peso molecular:450.40
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
170 nM
Compound: 2a
|
Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobilization by FLIPR assay
Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobilization by FLIPR assay
|
[PMID: 18573659] |
Chemical Information
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No. CAS 346729-66-6
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Peso molecular 450.40
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Fòrmula C23H29Cl2N3O2
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SMILES
O=C(C1=CC(Cl)=C(C=C1)Cl)N[C@@H](CC2)CN2CC3=CC=C(C=C3)OCCCN(C)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)