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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
57 Results for "
Trt
" in MedChemExpress (MCE) Product Catalog:
Products (57)
57 Results for "Trt" in MCE Product Catalog:
1
1 Cited Publications
Referencia número: HY-W010712
No. CAS: 109425-51-6
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1
1 Cited Publications
Referencia número: HY-W013081
No. CAS: 132327-80-1
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1 Cited Publications
Referencia número: HY-W010788
No. CAS: 32926-43-5
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Referencia número: HY-W007798
No. CAS: 103213-32-7
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Referencia número: HY-W002327
No. CAS: 132388-59-1
Referencia número: HY-W010714
No. CAS: 200623-62-7
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Referencia número: HY-W008876
No. CAS: 201531-88-6
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Referencia número: HY-W010734
No. CAS: 111061-56-4
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Referencia número: HY-W013155
No. CAS: 35146-32-8
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Referencia número: HY-W010724
No. CAS: 167015-11-4
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Referencia número: HY-173374
No. CAS: 3114056-16-2
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DOTAGA-FAP-2286-ALB is a derivative of Rofapitide tetraxetan (HY-147057). DOTAGA-FAP-2286-ALB is a selective fibroblast activation protein (FAP) inhibitor with an IC50 value of 67.5 nM. DOTAGA-FAP-2286-ALB enhances tumor retention via albumin interaction, prolonging blood circulation and improving radiometal complex stability (e.g., with 111In and 225Ac). DOTAGA-FAP-2286-ALB is promising for research of radionuclide therapy (TRT) of FAP-positive solid tumors .
Referencia número: HY-W142161
No. CAS: 1217840-61-3
Synonyms: Fmoc-MeHis(Trt)-OH
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Referencia número: HY-W011156
No. CAS: 27144-18-9
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Mpa(Trt) is a linker and thiol handle for tert-Boc solid phase peptide synthesis .
Referencia número: HY-W048697
No. CAS: 201532-01-6
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Phe-Lys(Trt)-PAB is a cathepsin B substrate, and a cleavable ADC linker. Phe-Lys(Trt)-PAB acts as a lysosomally cleavable substrate for cysteine protease cathepsin B, with cleavage enabling linked anticancer drug release via self-immolative spacer . Phe-Lys(Trt)-PAB can be used for synthesis of ADCs .
Referencia número: HY-W053550
No. CAS: 25840-82-8
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Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Referencia número: HY-W108518
No. CAS: 2061897-68-3
Synonyms: Boc-his(Trt)-aib-oh
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(S)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid (Boc-his(trt)-aib-ohol) is a drug intermediate for synthesis of various active compounds.
Referencia número: HY-W010719
No. CAS: 180570-71-2
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Lys(CO-C3-p-I-Ph)-OMe is a pharmacokinetic modifier (PK modifier) that can improve the PK properties of PSMA ligand molecules (such as Ac-PSMA-trillium). Lys(CO-C3-p-I-Ph)-OMe can increase the residence time of Ac-PSMA-trillium in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-OMe also reduces salivary gland absorption of Ac-PSMA-trillium, potentially extending its half-life. Ac-PSMA-trillium is a suitable PSMA-targeting compound that has different biological applications after modification with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
