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Referencia número: HY-13465A

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VCH-916 free base

3 Cited Publications

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Based on 3 publication(s) in Google Scholar

VCH-916 free base is a thiophene derivative and non-nucleoside inhibitor of HCV NS5B polymerase. VCH-916 free base binds to Thumb Site II. VCH-916 free base can be used for the research of hepatitis c virus (hcv) infection.

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No. CAS: 914778-92-0
Fòrmula: C₂₆H₃₇NO₄S
Peso molecular:459.64

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

VCH-916 free base Chemical Structure

No. CAS: 914778-92-0

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Descripciòn

In Vitro

VCH-916 free base acts as a well-tolerated non-nucleoside inhibitor of HCV NS5B polymerase that binds to the Thumb Site II pocket^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 914778-92-0
Peso molecular 459.64
Fòrmula C₂₆H₃₇NO₄S
SMILES

O=C(C1=C(N([C@H]2CC[C@H](OC)CC2)C([C@H]3CC[C@H](C)CC3)=O)C=C(C4=CCCCC4)S1)O
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Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

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Antiviral Res

Antiviral candidates against the hepatitis E virus (HEV) and their combinations inhibit HEV growth in in vitro. [Abstract]

2019 Oct:170:104570. PMID: 31362004
bioRxiv

2026 May 31.
bioRxiv

Linking sugar sensing to immunity in plants via O-glycosylation. [Abstract]

2026 May 10:2026.05.04.722566. PMID: 42146548

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Mayhoub AS, et al. Hepatitis C RNA-dependent RNA polymerase inhibitors: a review of structure-activity and resistance relationships; different scaffolds and mutations. Bioorg Med Chem. 2012;20(10):3150-3161. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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VCH-916 free base

3 Cited Publications

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VCH-916 free base

Publications Citing Use of MedChemExpress (MCE) VCH-916 free base

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Publications (3)

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VCH-916 free base Related Classifications

HY-13465A Related Classifications