VDR agonist 2
VDR agonist 2 (compound 16i) is a VDR (vitamin D receptor) agonist that can effectively inhibit TGF-β1-induced activation of hepatic stellate cells (HSC). VDR agonist 2 has significant anti-hepatic fibrosis effects both in vitro and in vivo.
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- No. CAS: 3052323-55-1
- Fòrmula: C20H21F3O3
- Peso molecular:366.37
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
VDR[1].
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| LX-2 | IC50 |
>30 μM
Compound: 16i
|
Cytotoxicity against human LX-2 cells by CCK-8 assay
Cytotoxicity against human LX-2 cells by CCK-8 assay
|
[PMID: 37406383] |
Chemical Information
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No. CAS 3052323-55-1
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Peso molecular 366.37
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Fòrmula C20H21F3O3
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SMILES
FC(F)(CCCOC1=CC=C(/C=C/C2=CC=C(C(CO)=C2)CO)C=C1)F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)