2. Cell Cycle/DNA Damage
  3. Eukaryotic Initiation Factor (eIF)
  4. GCN2 modulator-1

GCN2 modulator-1 (compound 3) has GCN2 inhibitory activity, with the IC50 value less than 0.05 μM. GCN2 modulator-1 plays an important role in anti-tumor research.

For research use only. We do not sell to patients.

GCN2 modulator-1 Chemical Structure

GCN2 modulator-1 Chemical Structure

CAS No. : 2803470-63-3

Size Price Stock Quantity
1 mg USD 620 In-stock
5 mg USD 1550 In-stock
10 mg USD 2680 In-stock
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Based on 1 publication(s) in Google Scholar

GCN2 modulator-1 Related Antibodies

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Description

GCN2 modulator-1 (compound 3) has GCN2 inhibitory activity, with the IC50 value less than 0.05 μM. GCN2 modulator-1 plays an important role in anti-tumor research[1].

Molecular Weight

508.89

Formula

C20H15ClF2N6O4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C2C=NC(C3=C(C=CC(NS(=O)(C4=CC(Cl)=CN=C4OC)=O)=C3F)F)=CN2C=N1)NC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 31.25 mg/mL (61.41 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9651 mL 9.8253 mL 19.6506 mL
5 mM 0.3930 mL 1.9651 mL 3.9301 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9651 mL 9.8253 mL 19.6506 mL 49.1265 mL
5 mM 0.3930 mL 1.9651 mL 3.9301 mL 9.8253 mL
10 mM 0.1965 mL 0.9825 mL 1.9651 mL 4.9127 mL
15 mM 0.1310 mL 0.6550 mL 1.3100 mL 3.2751 mL
20 mM 0.0983 mL 0.4913 mL 0.9825 mL 2.4563 mL
25 mM 0.0786 mL 0.3930 mL 0.7860 mL 1.9651 mL
30 mM 0.0655 mL 0.3275 mL 0.6550 mL 1.6376 mL
40 mM 0.0491 mL 0.2456 mL 0.4913 mL 1.2282 mL
50 mM 0.0393 mL 0.1965 mL 0.3930 mL 0.9825 mL
60 mM 0.0328 mL 0.1638 mL 0.3275 mL 0.8188 mL
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GCN2 modulator-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GCN2 modulator-12803470-63-3Eukaryotic Initiation Factor (eIF)general control nonderepressible kinase 2 (GCN2)Inhibitorinhibitorinhibit

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