NUP210 - nucleoporin 210 Gene

Also Known as GP210; POM210

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23225

About NUP210

Cytogenetic location: 3p25.1 Genomic coordinates (GRCh38): 3:13,316,235-13,420,322 (from NCBI)

This gene has 8 transcripts (splice variants), 208 orthologues and 1 paralogue. Broad expression in lymph node (RPKM 17.2), bone marrow (RPKM 15.9) and 22 other tissues.

Summary

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3. [provided by RefSeq, Jul 2013]

NUP210 Products (1)

mRNA Protein Name
NM_024923.4 NP_079199.2 nuclear pore membrane glycoprotein 210 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Cellular Component GO Annotation Evidence References Source
located in nuclear envelope IDA
IDA: Inferred from direct assay
24315095 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NUP210 Protein Structure

Big_2

Big_2: Bacterial Ig-like domain (group 2) (1082 - 1151)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1800
  • 1887 a.a.
Protein Preferred Names Protein Names

nuclear pore membrane glycoprotein 210

  • nuclear envelope pore membrane protein POM 210

NUP210 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NUP210 Q8TEM1 NOCT Homo sapiens Q9UK39
Anti Tag CoIP
33961781
Intra
NUP210 Q8TEM1 NOCT Homo sapiens Q9UK39
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant NUP210 Proteins

Cat. No. Product Name Accession Purity
HY-P72263 NUP210 Protein, Human (His) Q8TEM1-1 (L28-L238) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P77109 NUP210 Protein, Human (sf9, GST) Q8TEM1-1 (L1837-H1887) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Autoimmune Cholangitis

  • Autoimmune Cholangiopathy
Crest Syndrome
Chronic Cholangitis
Amelogenesis Imperfecta, Type Ie

  • Aih1

  • Amelogenesis Imperfecta Type 1e

  • AI1E

  • Amelogenesis Imperfecta, Hypoplastic/Hypomaturation, X-Linked 1

  • Amelogenesis Imperfecta, Hypomaturation Type, With Snow-Capped Teeth

  • Enamel Hypoplasia, X-Linked

  • Amelogenesis Imperfecta Type Ie

  • Amelogenesis Imperfecta Hypoplastic/Hypomaturation X-Linked 1

  • Enamel Hypoplasia X-Linked

  • Amelogenesis Imperfecta, X-Linked 1

  • Amelogenesis Imperfecta, Type 1e

  • Amelogenesis Imperfecta Hypomaturationtype With Snow-Capped Teeth

  • X-Linked Amelogenesis Imperfecta 1

  • X-Linked Amelogenesis Imperfecta Hypoplastic/Hypomaturation 1

  • X-Linked Enamel Hypoplasia

  • Amelogenesis Imperfecta X-Linked 1

  • Amelogenesis Imperfecta 1e

  • Amelogenesis Imperfecta, Hypoplastic/Hypomaturation Type 1e

  • Amelogenesis Imperfecta Hypomaturation Type With Snow-Capped Teeth

  • Xai

  • X-Linked Amelogenesis Imperfecta

  • Amelogenesis Imperfecta, Hypoplastic/Hypomaturation, X-Linked 2
Amelogenesis Imperfecta, Type Ib

  • AI1B

  • Aih2

  • Amelogenesis Imperfecta Type 1b

  • Amelogenesis Imperfecta Type Ib

  • Hereditary Localized Enamel Hypoplasia

  • Amelogenesis Imperfecta - Hypoplastic Autosomal Dominant - Local

  • Amelogenesis Imperfecta, Hypoplastic Local, Autosomal Dominant

  • Enamel Hypoplasia, Hereditary Localized

  • Autosomal Dominant Hypoplastic Local Amelogenesis Imperfecta

  • Amelogenesis Imperfecta 1b

  • Amelogenesis Imperfecta Hypoplastic 2

  • Amelogenesis Imperfecta Hypoplastic Local Autosomal Dominant
Suppurative Cholangitis
Peliosis Hepatis

  • Hepatic Peliosis

  • Telangiectasis Of Liver

  • Angiomatosis Of Liver

  • Ph - [Peliosis Hepatis]

  • Hepatic Angiomatosis
Achalasia-Addisonianism-Alacrima Syndrome

  • Allgrove Syndrome

  • Triple-A Syndrome

  • Achalasia-Addisonianism-Alacrimia Syndrome

  • Alacrima-Achalasia-Adrenal Insufficiency Neurologic Disorder

  • Triple A Syndrome

  • Aaa Syndrome

  • AAAS

  • Glucocorticoid Deficiency With Achalasia

  • Glucocorticoid Deficiency And Achalasia

  • Addisonian-Achalasia Syndrome

  • Hypoadrenalism With Achalasia

  • Alacrima-Achalasia-Addisonianism

  • Aaa

  • Acth-Resistant Adrenal Insufficiency, Achalasia And Alacrima

  • Achalasia Addisonianism Alacrimia Syndrome

  • Achalasia Alacrima Syndrome

  • Addisonian Achalasia Syndrome

  • Achalasia-Addisonian Syndrome

  • Achalasia-Alacrima Syndrome

  • 2a Syndrome

  • 3a Syndrome

  • 4a Syndrome

  • Adrenal Insufficiency-Achalasia-Alacrima Syndrome

  • Double A Syndrome

  • Quaternary A Syndrome

  • Acth-Resistant Adrenal Insufficiency With Achalasia And Alacrima

  • Allgrove'S Syndrome

  • Adrenal Gland Hypofunction

  • Adrenal Cortical Hypofunction
Sclerosing Cholangitis

  • Fibrosing Cholangitis

  • Cholangitis, Sclerosing

  • Primary Sclerosing Cholangitis
Autoimmune Disease Of Gastrointestinal Tract
Cholangitis, Primary Sclerosing

  • Primary Sclerosing Cholangitis

  • PSC

  • Sclerosing Cholangitis

  • Cholangitis, Sclerosing

  • Cholangitis Primary Sclerosing

  • Psc - [Primary Sclerosing Cholangitis]
Primary Biliary Cholangitis

  • Primary Biliary Cirrhosis

  • Biliary Liver Cirrhosis

  • Chronic Nonsuppurative Destructive Cholangitis

  • Familial Primary Biliary Cirrhosis

  • Pbc

  • Hanot Syndrome

  • Cholestatic Cirrhosis

  • Biliary Cirrhosis Primary

  • Liver Cirrhosis, Biliary

  • Hanot'S Cirrhosis

  • Biliary Cirrhosis

  • Pericholangiolic Biliary Cirrhosis

  • Tannhauser-Magendantz Syndrome

  • Hanot-Rossle Syndrome

  • Hypertrophic Cirrhosis

  • Todd Cirrhosis

  • Hanot Cirrhosis

  • Charcot Cirrhosis

  • Mahon-Tannhauser Syndrome

  • Toxic Cirrhosis

  • Hypertrophic Biliary Cirrhosis

  • Monolobular Cirrhosis

  • Unilobar Cirrhosis

  • Xanthomatous Biliary Cirrhosis
Limited Scleroderma

  • Limited Cutaneous Systemic Sclerosis

  • Limited Systemic Sclerosis

  • Systemic Sclerosis Sine Scleroderma

  • Crest Syndrome

  • Limited Cutaneous Systemic Scleroderma

  • Scleroderma, Limited

  • Systemic Sclerosis, Limited

  • Progressive Systemic Sclerosis Sine Scleroderma

  • Scleroderma, Sine

  • Crest - [Calcinosis, Raynaud Phenomenon, Oesophageal Dysmotility, Sclerodactyly, And Telangiectasia] Syndrome

  • Crst - [Calcinosis, Raynaud Phenomenon, Sclerodactyly And Telangiectasia] Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09690 NUP210 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09691 NUP210L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19069 Nup210 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25559 Nup210 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NUP210 VGNC VGNC:75494
Felis catus NUP210 VGNC VGNC:63922
Mus musculus NUP210 MGD MGI:1859555
Rattus norvegicus NUP210 RGD RGD:69339
Bos taurus NUP210 VGNC VGNC:32356
Canis familiaris NUP210 VGNC VGNC:44050
Others NUP210 NCBI