Trhr - thyrotropin releasing hormone receptor Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25570

Summary

Enables identical protein binding activity and thyrotropin-releasing hormone receptor activity. Involved in positive regulation of cytosolic calcium ion concentration and positive regulation of protein-containing complex assembly. Located in cell surface. Used to study hypertension. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 7 and hypertension. Orthologous to human TRHR (thyrotropin releasing hormone receptor). [provided by Alliance of Genome Resources, Apr 2022]

Trhr Products (1)

mRNA Protein Name
NM_013047.3 NP_037179.1 thyrotropin-releasing hormone receptor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
12023974 RGD
enables thyrotropin-releasing hormone receptor activity IDA
IDA: Inferred from direct assay
12023974 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
12023974 RGD
involved in positive regulation of protein-containing complex assembly IDA
IDA: Inferred from direct assay
12023974 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
12023974 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thyrotropin-releasing hormone receptor

  • TRH-R

  • thyroliberin receptor

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0596 Taltirelin 99.91% Unkown
HY-B0596A Taltirelin acetate 99.75% Unkown

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W331198 Tralopyril Inducer 99.70% Unkown
HY-B0596S Taltirelin-13C,d3 / Unkown
HY-RS15013 TRHR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20348 Trhr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26857 Trhr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trhr NCBI NCBI:7201