HIGD1A - HIG1 hypoxia inducible domain family member 1A Gene
Also Known as HIG1; RCF1a
Species: Homo sapiens
About HIGD1A
This gene has 5 transcripts (splice variants), 191 orthologues and 4 paralogues. Ubiquitous expression in colon (RPKM 73.6), heart (RPKM 47.7) and 24 other tissues.
Summary
Acts upstream of or within negative regulation of apoptotic process. Located in mitochondrion and nucleoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]
HIGD1A Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001099668.2 | NP_001093138.1 | HIG1 domain family member 1A, mitochondrial isoform a |
| NM_001099669.2 | NP_001093139.1 | HIG1 domain family member 1A, mitochondrial isoform b |
| NM_014056.4 | NP_054775.2 | HIG1 domain family member 1A, mitochondrial isoform b |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within negative regulation of apoptotic process |
IDA
IDA: Inferred from direct assay
|
21856340 | GOA |
HIGD1A Protein Structure
HIG_1_N: Hypoxia induced protein conserved region (24 - 78)
- 0
- 93 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
HIG1 domain family member 1A, mitochondrial |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Cecum Adenocarcinoma |
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| Colon Mucinous Adenocarcinoma |
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| Mitochondrial Trifunctional Protein Deficiency |
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| 3-Methylglutaconic Aciduria, Type Iii |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | HIGD1A | MGD | MGI:1930666 |
| Rattus norvegicus | HIGD1A | RGD | RGD:620215 |
| Others | HIGD1A | NCBI |