THYN1 - thymocyte nuclear protein 1 Gene

Also Known as MY105; THY28; MDS012; HSPC144; THY28KD

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 29087

About THYN1

Cytogenetic location: 11q25 Genomic coordinates (GRCh38): 11:134,248,282-134,253,352 (from NCBI)

This gene has 8 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in thyroid (RPKM 21.0), ovary (RPKM 20.9) and 25 other tissues.

Summary

This gene encodes a protein that is highly conserved among vertebrates and plant species and may be involved in the induction of Apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

THYN1 Products (5)

mRNA Protein Name
NM_001037304.2 NP_001032381.1 thymocyte nuclear protein 1 isoform 2
NM_001037305.2 NP_001032382.1 thymocyte nuclear protein 1 isoform 1
NM_014174.3 NP_054893.1 thymocyte nuclear protein 1 isoform 1
NM_199297.2 NP_954994.1 thymocyte nuclear protein 1 isoform 2
NM_199298.2 NP_954995.1 thymocyte nuclear protein 1 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

THYN1 Protein Structure

EVE

EVE: EVE domain (56 - 218)

  • 0
  • 100
  • 200
  • 225 a.a.
Protein Preferred Names Protein Names

thymocyte nuclear protein 1

  • thymocyte protein thy28

THYN1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
THYN1 Q9P016 SHPK Homo sapiens Q9UHJ6
Anti Tag CoIP
33961781
Intra
THYN1 Q9P016 SHPK Homo sapiens Q9UHJ6
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Jacobsen Syndrome

  • Chromosome 11q Deletion Syndrome

  • Partial 11q Monosomy Syndrome

  • Jacobsen Distal 11q Deletion Syndrome

  • JBS

  • 11q Partial Monosomy Syndrome

  • Chromosome 11q Deletion

  • 11q Deletion

  • 11q Monosomy

  • Deletion 11q

  • Monosomy 11q

  • Partial Monosomy 11q

  • 11q Deletion Disorder

  • 11q Deletion Syndrome

  • 11q Terminal Deletion Disorder

  • 11q- Deletion Syndrome

  • 11q23 Deletion Disorder

  • Jacobsen Thrombocytopenia

  • 11q Terminal Deletion Syndrome

  • Del(11)(Q23.3)

  • Del(11)(Qter)

  • Distal Deletion 11q

  • Distal Monosomy 11q

  • Monosomy 11qter

  • Telomeric Deletion 11q

  • Paris-Trousseau Thrombocytopenia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14512 THYN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22859 Thyn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29373 Thyn1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus THYN1 RGD RGD:1359525
Canis familiaris THYN1 VGNC VGNC:53457
Bos taurus THYN1 VGNC VGNC:35857
Mus musculus THYN1 MGD MGI:1925112
Felis catus THYN1 VGNC VGNC:103752
Macaca mulatta THYN1 VGNC VGNC:110528
Others THYN1 NCBI