2. Gene
  3. Abca4 - ATP binding cassette subfamily A member 4 Gene

Abca4 - ATP binding cassette subfamily A member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as ABCR

Gene ID: 310836 | Gene type: protein coding

About Abca4

Summary

Predicted to enable ATPase-coupled transmembrane transporter activity; glycerophospholipid flippase activity; and retinal binding activity. Predicted to be involved in phospholipid translocation and retinal metabolic process. Predicted to act upstream of or within phospholipid transfer to membrane; photoreceptor cell maintenance; and visual perception. Predicted to be located in cytoplasmic vesicle; endoplasmic reticulum; and photoreceptor outer segment. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in fundus dystrophy and retinal degeneration (multiple). Orthologous to human ABCA4 (ATP binding cassette subfamily A member 4). [provided by Alliance of Genome Resources, Apr 2022]

Abca4 Products(1)

mRNA Protein Name
NM_001107721.1 NP_001101191.1 retinal-specific phospholipid-transporting ATPase ABCA4
Protein Preferred Names Protein Names

retinal-specific phospholipid-transporting ATPase ABCA4

ATP-binding cassette, sub-family A (ABC1), member 4

ATP-binding cassette, subfamily A (ABC1), member 4

retinal-specific ATP-binding cassette transporter

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W004500 All-trans-retinal Inducer 99.56% Unkown
HY-183032 ABC transporter modulator-1 Activator / Unkown
HY-183033 ABC transporter modulator-2 Activator / Unkown
HY-183034 ABC transporter modulator-3 Activator / Unkown
HY-175664 EYE-003 Inhibitor / Unkown
HY-183035 ABC transporter modulator-4 Modulator / Unkown
HY-183036 ABC transporter modulator-5 Modulator / Unkown
HY-RS00042 ABCA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abca4 NCBI NCBI:24