ABC transporter modulator-1
Based on 1 Customer Validation
ABC transporter modulator-1 (Compound I-5) is an ABC transporter expression enhancer. ABCC6 modulator-1 upregulates the expression of wild-type ABCC6, wild-type ABCB4, and ABCA4P1380L mutant, with an EC50 of <1 μM for all.
For research use only. We do not sell to patients.
- Purity: 96.30%
- CAS No.: 3093661-22-1
- Formula: C20H19N5O3S
- Molecular Weight:409.46
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ABC transporter modulator-1 upregulates the expression of wild-type ABCC6 with an EC50 of <1 μM[1].
ABC transporter modulator-1 upregulates the expression of wild-type ABCC4 with an EC50 of <1 μM[1].
ABC transporter modulator-1 increases the expression of ABCA4P1380L, with an EC50 of <1 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3093661-22-1
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Appearance Solid
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Molecular Weight 409.46
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Formula C20H19N5O3S
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Color Off-white to light brown
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SMILES
N#CC1=CC(C2=CC=C(NS(=O)(C)=O)C(OC3=C(C)C=C(C)N=C3C)=N2)=CN=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 10 mg/mL (24.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4422 mL | 12.2112 mL | 24.4224 mL | 61.0560 mL |
| 5 mM | 0.4884 mL | 2.4422 mL | 4.8845 mL | 12.2112 mL | |
| 10 mM | 0.2442 mL | 1.2211 mL | 2.4422 mL | 6.1056 mL | |
| 15 mM | 0.1628 mL | 0.8141 mL | 1.6282 mL | 4.0704 mL | |
| 20 mM | 0.1221 mL | 0.6106 mL | 1.2211 mL | 3.0528 mL |
ABC transporter modulator-1 Related Classifications
HY-183032 Related Classifications
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