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Referencia número: HY-183032

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ABC transporter modulator-1

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Based on 1 Customer Validation

ABC transporter modulator-1 (Compound I-5) is an ABC transporter expression enhancer. ABCC6 modulator-1 upregulates the expression of wild-type ABCC6, wild-type ABCB4, and ABCA4^P1380L mutant, with an EC₅₀ of <1 μM for all.

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 96.30%
No. CAS: 3093661-22-1
Fòrmula: C₂₀H₁₉N₅O₃S
Peso molecular:409.46

Almacenamiento:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

ABC transporter modulator-1 Chemical Structure

No. CAS: 3093661-22-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
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- In Vitro
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Actividad biológica

Descripciòn

In Vitro

ABC transporter modulator-1 upregulates the expression of wild-type ABCC6 with an EC₅₀ of <1 μM^[1].
ABC transporter modulator-1 upregulates the expression of wild-type ABCC4 with an EC₅₀ of <1 μM^[1].
ABC transporter modulator-1 increases the expression of ABCA4^P1380L, with an EC₅₀ of <1 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 3093661-22-1
Appearance Solid
Peso molecular 409.46
Fòrmula C₂₀H₁₉N₅O₃S
Color Off-white to light brown
SMILES

N#CC1=CC(C2=CC=C(NS(=O)(C)=O)C(OC3=C(C)C=C(C)N=C3C)=N2)=CN=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (272 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Nathan Oliver Fuller, et al. Pyridinyloxypyridines as modulators of atp -binding cassette transporters and their use in treating medical conditions. WO2025151724A1. WIPO (PCT). 2025-01-10.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

ABC transporter modulator-1

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ABC transporter modulator-1

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Bioactive Compound Library

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Membrane Transporter/Ion Channel Compound Library

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ABC transporter modulator-1

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Membrane Transporter/Ion Channel Compound Library

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

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ABC transporter modulator-1 Related Classifications

HY-183032 Related Classifications