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Cat. No.: HY-183032

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ABC transporter modulator-1

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ABC transporter modulator-1 (Compound I-5) is an ABC transporter expression enhancer. ABCC6 modulator-1 upregulates the expression of wild-type ABCC6, wild-type ABCB4, and ABCA4^P1380L mutant, with an EC₅₀ of <1 μM for all.

For research use only. We do not sell to patients.

Purity: 96.30%
CAS No.: 3093661-22-1
Formula: C₂₀H₁₉N₅O₃S
Molecular Weight:409.46

Storage:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

ABC transporter modulator-1 Chemical Structure

CAS No.: 3093661-22-1

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

In Vitro

ABC transporter modulator-1 upregulates the expression of wild-type ABCC6 with an EC₅₀ of <1 μM^[1].
ABC transporter modulator-1 upregulates the expression of wild-type ABCC4 with an EC₅₀ of <1 μM^[1].
ABC transporter modulator-1 increases the expression of ABCA4^P1380L, with an EC₅₀ of <1 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3093661-22-1
Appearance Solid
Molecular Weight 409.46
Formula C₂₀H₁₉N₅O₃S
Color Off-white to light brown
SMILES

N#CC1=CC(C2=CC=C(NS(=O)(C)=O)C(OC3=C(C)C=C(C)N=C3C)=N2)=CN=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nathan Oliver Fuller, et al. Pyridinyloxypyridines as modulators of atp -binding cassette transporters and their use in treating medical conditions. WO2025151724A1. WIPO (PCT). 2025-01-10.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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