ABC transporter modulator-3
Based on 1 Customer Validation
ABCC6 modulator-3 (Compound I-71) is a ABCC6 activator with an EC50 < 1 μM. ABCC6 modulator-3 upregulates the expression of wild-type ABCC6. ABCC6 modulator-3 is used in research on diseases associated with ABC transporter dysfunction.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 3093661-88-9
- Formula: C24H21ClN4O3S
- Molecular Weight:480.97
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ABC transporter modulator-3 potently increases the expression level of ABCC6 WT, with an EC50 < 1 μM[1].
ABC transporter modulator-3 fails to effectively upregulate the expression of ABCB4 WT, with an EC50 ≥ 25 μM[1].
ABC transporter modulator-3 fails to effectively increase the expression level of ABCA4P1380L, with an EC50 ≥ 25 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3093661-88-9
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Appearance Solid
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Molecular Weight 480.97
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Formula C24H21ClN4O3S
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Color White to off-white
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SMILES
O=S(NC1=CC=C(C2=CN=CC(Cl)=C2)N=C1OC3=C(C)C=C(C)C=C3C)(C4=CC=CN=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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