ABC transporter modulator-3
Based on 1 Customer Validation
ABCC6 modulator-3 (Compound I-71) is a ABCC6 activator with an EC50 < 1 μM. ABCC6 modulator-3 upregulates the expression of wild-type ABCC6. ABCC6 modulator-3 is used in research on diseases associated with ABC transporter dysfunction.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 3093661-88-9
- Formula: C24H21ClN4O3S
- Molecular Weight:480.97
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ABC transporter modulator-3 potently increases the expression level of ABCC6 WT, with an EC50 < 1 μM[1].
ABC transporter modulator-3 fails to effectively upregulate the expression of ABCB4 WT, with an EC50 ≥ 25 μM[1].
ABC transporter modulator-3 fails to effectively increase the expression level of ABCA4P1380L, with an EC50 ≥ 25 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3093661-88-9
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Appearance Solid
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Molecular Weight 480.97
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Formula C24H21ClN4O3S
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Color White to off-white
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SMILES
O=S(NC1=CC=C(C2=CN=CC(Cl)=C2)N=C1OC3=C(C)C=C(C)C=C3C)(C4=CC=CN=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 51 mg/mL (106.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0791 mL | 10.3957 mL | 20.7913 mL | 51.9783 mL |
| 5 mM | 0.4158 mL | 2.0791 mL | 4.1583 mL | 10.3957 mL | |
| 10 mM | 0.2079 mL | 1.0396 mL | 2.0791 mL | 5.1978 mL | |
| 15 mM | 0.1386 mL | 0.6930 mL | 1.3861 mL | 3.4652 mL | |
| 20 mM | 0.1040 mL | 0.5198 mL | 1.0396 mL | 2.5989 mL | |
| 25 mM | 0.0832 mL | 0.4158 mL | 0.8317 mL | 2.0791 mL | |
| 30 mM | 0.0693 mL | 0.3465 mL | 0.6930 mL | 1.7326 mL | |
| 40 mM | 0.0520 mL | 0.2599 mL | 0.5198 mL | 1.2995 mL | |
| 50 mM | 0.0416 mL | 0.2079 mL | 0.4158 mL | 1.0396 mL | |
| 60 mM | 0.0347 mL | 0.1733 mL | 0.3465 mL | 0.8663 mL | |
| 80 mM | 0.0260 mL | 0.1299 mL | 0.2599 mL | 0.6497 mL | |
| 100 mM | 0.0208 mL | 0.1040 mL | 0.2079 mL | 0.5198 mL |
ABC transporter modulator-3 Related Classifications
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