ABC transporter modulator-3

Cat. No.: HY-183034: Data Sheet Handling Instructions
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ABCC6 modulator-3 (Compound I-71) is a ABCC6 activator with an EC₅₀ < 1 μM. ABCC6 modulator-3 upregulates the expression of wild-type ABCC6. ABCC6 modulator-3 is used in research on diseases associated with ABC transporter dysfunction.

For research use only. We do not sell to patients.

ABC transporter modulator-3 Chemical Structure

CAS No. : 3093661-88-9

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5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
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Description	ABCC6 modulator-3 (Compound I-71) is a ABCC6 activator with an EC₅₀ < 1 μM. ABCC6 modulator-3 upregulates the expression of wild-type ABCC6. ABCC6 modulator-3 is used in research on diseases associated with ABC transporter dysfunction^[1].
In Vitro	ABC transporter modulator-3 potently increases the expression level of ABCC6 WT, with an EC₅₀ < 1 μM^[1]. ABC transporter modulator-3 fails to effectively upregulate the expression of ABCB4 WT, with an EC₅₀ ≥ 25 μM^[1]. ABC transporter modulator-3 fails to effectively increase the expression level of ABCA4^P1380L, with an EC₅₀ ≥ 25 μM^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. ABC transporter modulator-3 Related Antibodies
Molecular Weight	480.97
Formula	C₂₄H₂₁ClN₄O₃S
CAS No.	3093661-88-9
Appearance	Solid
SMILES	O=S(NC1=CC=C(C2=CN=CC(Cl)=C2)N=C1OC3=C(C)C=C(C)C=C3C)(C4=CC=CN=C4)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation	Data Sheet (272 KB) Handling Instructions (2659 KB)
References	[1]. Nathan Oliver Fuller, et al. Pyridinyloxypyridines as modulators of atp -binding cassette transporters and their use in treating medical conditions. WO2025151724A1. WIPO (PCT). 2025-01-10.