2. Gene
  3. Mir155 - microRNA 155 Gene

Mir155 - microRNA 155 Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mirn155; mir-155; mmu-mir-155

Gene ID: 387173 | Gene type: ncRNA

About Mir155

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to amino acid stimulus IDA
IDA: Inferred from direct assay
20548288 MGI
acts upstream of or within cellular response to dexamethasone stimulus IEP
IEP: Inferred from expression pattern
24391219 MGI
acts upstream of or within cellular response to granulocyte macrophage colony-stimulating factor stimulus IEP
IEP: Inferred from expression pattern
24391219 MGI
acts upstream of or within cellular response to interleukin-6 IEP
IEP: Inferred from expression pattern
24391219 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
18762567 MGI
acts upstream of or within cellular response to transforming growth factor beta stimulus IEP
IEP: Inferred from expression pattern
24391219 MGI
acts upstream of or within hematopoietic stem cell differentiation IDA
IDA: Inferred from direct assay
20660734 MGI
acts upstream of or within inflammatory response to antigenic stimulus IDA
IDA: Inferred from direct assay
22517757 MGI
acts upstream of or within miRNA-mediated post-transcriptional gene silencing IDA
IDA: Inferred from direct assay
20548288 MGI
acts upstream of or within negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
22517757 MGI
acts upstream of or within positive regulation of cell growth IDA
IDA: Inferred from direct assay
24391219 MGI
acts upstream of or within positive regulation of cell growth IGI
IGI: Inferred from genetic interaction
24391219 MGI
acts upstream of or within positive regulation of type II interferon production IMP
IMP: Inferred from mutant phenotype
22517757 MGI
acts upstream of or within response to oxygen levels IDA
IDA: Inferred from direct assay
18723672 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-132601A Cobomarsen sodium 99.29% Phase 2
HY-132601 Cobomarsen Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153713 MYC-RIBOTAC 98.17% Unkown
HY-R00316 hsa-miR-155-5p mimic 99.53% Unkown
HY-R02691 mmu-miR-155-5p mimic 97.93% Unkown
HY-RI02691 mmu-miR-155-5p inhibitor 97.03% Unkown
HY-RI00316 hsa-miR-155-5p inhibitor 99.48% Unkown
HY-RI00316A hsa-miR-155-5p antagomir 96.01% Unkown
HY-R00316A hsa-miR-155-5p agomir 99.68% Unkown
HY-RI02691A mmu-miR-155-5p antagomir 98.32% Unkown
HY-R02691A mmu-miR-155-5p agomir 93.99% Unkown
HY-179344 Benzazepinoquinoline-spermine Inhibitor / Unkown
HY-P11698 Guanidino-G-Clamp-PNA Inhibitor / Unkown
HY-R00315 hsa-miR-155-3p mimic / Unkown
HY-R00315A hsa-miR-155-3p agomir / Unkown
HY-RI00315 hsa-miR-155-3p inhibitor / Unkown
HY-RI00315A hsa-miR-155-3p antagomir / Unkown
HY-132601C Cobomarsen scrambled control / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir155 NCBI NCBI:406947