RSL24D1 - ribosomal L24 domain containing 1 Gene

Also Known as L30; RLP24; RPL24; TVAS3; RPL24L; C15orf15; HRP-L30-iso

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51187

About RSL24D1

Cytogenetic location: 15q21.3 Genomic coordinates (GRCh38): 15:55,180,806-55,196,941 (from NCBI)

This gene has 12 transcripts (splice variants), 206 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 88.8), ovary (RPKM 69.7) and 25 other tissues.

Summary

This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The protein encoded by this gene localizes to the nucleolus and is thought to play a role in the biogenesis of the 60S ribosomal subunit. The precise function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals and has multiple pseudogenes. [provided by RefSeq, Jul 2012]

RSL24D1 Products (1)

mRNA Protein Name
NM_016304.3 NP_057388.1 probable ribosome biogenesis protein RLP24

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RSL24D1 Protein Structure

Ribosomal_L24e

Ribosomal_L24e: Ribosomal protein L24e (1 - 64)

  • 0
  • 100
  • 163 a.a.
Protein Preferred Names Protein Names

probable ribosome biogenesis protein RLP24

  • 60S ribosomal protein L30 isolog

RSL24D1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RSL24D1 Q9UHA3 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
25416956
Intra
RSL24D1 Q9UHA3 FAM9B Homo sapiens Q8IZU0
Y2H Array
25416956
Intra
RSL24D1 Q9UHA3 CDC23 Homo sapiens Q9UJX2
Validated Y2H
25416956
Intra
RSL24D1 Q9UHA3 DNMT3L Homo sapiens Q9UJW3
Y2H Array
32296183
Intra
RSL24D1 Q9UHA3 DNMT3L Homo sapiens Q9UJW3
Validated Y2H
32296183
Intra
RSL24D1 Q9UHA3 DNMT3L Homo sapiens Q9UJW3
Y2H Prey Pooling
25416956
Intra
RSL24D1 Q9UHA3 DNMT3L Homo sapiens Q9UJW3
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Diamond-Blackfan Anemia

  • Congenital Pure Red Cell Aplasia

  • Aase Syndrome

  • Erythrogenesis Imperfecta

  • Anemia, Diamond-Blackfan

  • Congenital Hypoplastic Anemia

  • Aase-Smith Ii Syndrome

  • Bds

  • Blackfan-Diamond Anemia

  • Congenital Prca

  • Congenital Hypoplastic Anemia, Blackfan-Diamond Type

  • Dba

  • Blackfan - Diamond Syndrome

  • Chronic Constitutional Pure Red Cell Anaemia

  • Anemia Diamond Blackfan Type

  • Anemia Congenital Erythroid Hypoplastic

  • Aregenerative Anemia Chronic Congenital

  • Blackfan Diamond Syndrome

  • Red Cell Aplasia, Pure Hereditary

  • Aase-Smith Syndrome Ii

  • Bda

  • Blackfan Diamond Anemia

  • Blackfan-Diamond Disease

  • Blackfan-Diamond Syndrome

  • Chronic Congenital Agenerative Anemia

  • Congenital Erythroid Hypoplastic Anemia

  • Congenital Hypoplastic Anemia Of Blackfan And Diamond

  • Congenital Pure Red Cell Anemia

  • Hypoplastic Congenital Anemia

  • Inherited Erythroblastopenia

  • Pure Hereditary Red Cell Aplasia

  • Anemia, Hypoplastic, Congenital

  • Anemia Hypoplastic Congenital

  • Fanconi Anemia

  • Constitutional Aplastic Anemia

  • Diamond-Blackfan Anemia 1

  • Aase Smith Syndrome 2

  • Congenital Red Cell Aplasia

  • Red Cell Aplasia Of Infants

  • Pure Red Cell Aplasia Of Infants

  • Congenital Red Cell Aplastic Anaemia

  • Congenital Pure Red Cell Anaemia

  • Congenital Erythroid Hypoplasia

  • Pearson Marrow-Pancreas Syndrome
Shwachman-Diamond Syndrome 1

  • Shwachman-Diamond Syndrome

  • Shwachman Syndrome

  • Shwachman-Bodian-Diamond Syndrome

  • Sds

  • Pancreatic Insufficiency And Bone Marrow Dysfunction

  • Shwachman-Bodian Syndrome

  • SDS1

  • Lipomatosis Of Pancreas, Congenital

  • Congenital Lipomatosis Of Pancreas

  • Shwachman-Diamond Type Metaphyseal Dysplasia

  • Metaphyseal Chondrodysplasia, Shwachman Type

  • Shwachman-Diamond-Oski Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12301 RSL24D1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RSL24D1 RGD RGD:1309784
Canis familiaris RSL24D1 VGNC VGNC:45776
Bos taurus RSL24D1 VGNC VGNC:34181
Mus musculus RSL24D1 MGD MGI:2681840
Macaca mulatta RSL24D1 VGNC VGNC:99234
Felis catus RSL24D1 VGNC VGNC:104715
Others RSL24D1 NCBI