ERGIC2 - ERGIC and golgi 2 Gene

Also Known as PTX1; CDA14; Erv41; cd002

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51290

Summary

ERGIC2, or PTX1, is a ubiquitously expressed nuclear protein that is downregulated in prostate carcinoma (Kwok et al., 2001 [PubMed 11445006]).[supplied by OMIM, Aug 2008]
Ubiquitous expression in urinary bladder (RPKM 7.7), placenta (RPKM 7.5) and 25 other tissues.

ERGIC2 Products (1)

mRNA Protein Name
NM_016570.3 NP_057654.2 endoplasmic reticulum-Golgi intermediate compartment protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17980171 GOA
Biological Process GO Annotation Evidence References Source
involved in endoplasmic reticulum to Golgi vesicle-mediated transport IDA
IDA: Inferred from direct assay
31142615 GOA
involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IMP
IMP: Inferred from mutant phenotype
24768165 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17980171 GOA
located in nucleus IDA
IDA: Inferred from direct assay
17980171 GOA
part of retrograde transporter complex, Golgi to ER IPI
IPI: Inferred from physical interaction
31142615 GOA
part of transporter complex IPI
IPI: Inferred from physical interaction
31142615 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ERGIC2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ERGIC2 Q96RQ1 ERGIC3 Homo sapiens Q9Y282
Anti Tag CoIP
31142615
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-117744 NMS-P645 Inhibitor / Unkown