CHST15 - carbohydrate sulfotransferase 15 Gene

Homo sapiens

Also known as BRAG; GALNAC4S-6ST

Gene ID: 51363 | Gene type: protein coding

About CHST15

Cytogenetic location: 10q26.13 Genomic coordinates (GRCh38): 10:124,007,668-124,093,598 (from NCBI)

This gene has 5 transcripts (splice variants) and 266 orthologues. Ubiquitous expression in ovary (RPKM 9.9), spleen (RPKM 9.5) and 25 other tissues.

Summary

Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

CHST15 Products(4)

mRNA	Protein	Name
NM_001270764.2	NP_001257693.1	carbohydrate sulfotransferase 15 isoform 1
NM_001270765.2	NP_001257694.1	carbohydrate sulfotransferase 15 isoform 2
NM_014863.4	NP_055678.2	carbohydrate sulfotransferase 15 isoform 2
NM_015892.5	NP_056976.2	carbohydrate sulfotransferase 15 isoform 1

CHST15 Protein Structure

Sulfotransfer_1

0
100
200
300
400
500
561 a.a.

Protein Preferred Names

Protein Names

carbohydrate sulfotransferase 15

B cell RAG associated protein (GALNAC4S-6ST)

Recombinant CHST15 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76258	CHST15 Protein, Human (HEK293, His)	Q7LFX5 (S99-T561)	≥95%

Related Diseases

Diseases

Alias

Spondyloepiphyseal Dysplasia With Congenital Joint Dislocations

Spondyloepiphyseal Dysplasia	Chst3-Related Skeletal Dysplasia
Humerospinal Dysostosis	Spondyloepiphyseal Dysplasia, Omani Type
Chondrodysplasia With Multiple Dislocations	SEDCJD
Hsd	Cdmd
Humero-Spinal Dysostosis	Kozlowski Celermajer Tink Syndrome
Chondrodysplasia With Congenital Joint Dislocations, Chst3 Type	Larsen Syndrome, Recessive Type
Humero-Spinal Dysostosis With Congenital Heart Disease	Omani Type
Sed	Chst3 Deficiency
Chst3-Related Dysplasia	Recessive Larsen Syndrome
Autosomal Recessive Larsen Syndrome	Sed With Luxations, Chst3 Type
Sed, Omani Type	Sdcd, Chst3 Type
Spondyloepiphyseal Dysplasia With Congenital Joint Dyslocations, Chst3 Type	Sed Omani Type
Spondyloepiphyseal Dysplasia Omani Type	Larsen Syndrome, Autosomal Recessive
Mucopolysaccharidosis Iv	Spondyloepiphyseal Dysplasia, Congenita

Larsen Syndrome

LRS	Larsen Syndrome, Dominant Type
Dominant Larsen Syndrome	Autosomal Dominant Larsen Syndrome
Larsens Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-124704	Chst15-IN-1		98.09%	Unkown
HY-RS02687	CHST15 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CHST15	MGD	MGI:1924840
Rattus norvegicus	CHST15	RGD	RGD:628881
Bos taurus	CHST15	VGNC	VGNC:27343
Macaca mulatta	CHST15	VGNC	VGNC:70999
Felis catus	CHST15	VGNC	VGNC:60889
Canis familiaris	CHST15	VGNC	VGNC:39253
Others	CHST15	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.