CNDP2 - carnosine dipeptidase 2 Gene

Homo sapiens

Also known as CN2; CPGL; PEPA; HsT2298; HEL-S-13

Gene ID: 55748 | Gene type: protein coding

About CNDP2

Cytogenetic location: 18q22.3 Genomic coordinates (GRCh38): 18:74,496,363-74,523,454 (from NCBI)

This gene has 29 transcripts (splice variants), 223 orthologues and 3 paralogues. Ubiquitous expression in kidney (RPKM 58.4), small intestine (RPKM 41.5) and 24 other tissues.

Summary

CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008]

CNDP2 Products(6)

mRNA	Protein	Name
NM_001168499.2	NP_001161971.1	cytosolic non-specific dipeptidase isoform 2
NM_001370248.1	NP_001357177.1	cytosolic non-specific dipeptidase isoform 1
NM_001370249.1	NP_001357178.1	cytosolic non-specific dipeptidase isoform 1
NM_001370250.1	NP_001357179.1	cytosolic non-specific dipeptidase isoform 1
NM_001370254.1	NP_001357183.1	cytosolic non-specific dipeptidase isoform 3
NM_018235.3	NP_060705.2	cytosolic non-specific dipeptidase isoform 1

CNDP2 Protein Structure

Peptidase_M20

M20_dimer

0
100
200
300
400
475 a.a.

Protein Preferred Names

Protein Names

cytosolic non-specific dipeptidase

CNDP dipeptidase 2 (metallopeptidase M20 family)

Recombinant CNDP2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76837	CNDP2 Protein, Human (sf9, His)	Q96KP4 (M1-D475)	≥95%

Related Diseases

Diseases

Alias

Penile Cancer

Penis Carcinoma	Carcinoma Of Penis
Penile Neoplasm	Penile Carcinoma
Penile Neoplasms	Malignant Neoplasm Of Penis
Ca Penis	Malignant Neoplasm Of Body Of Penis
Malignant Penile Tumor	Penile Ca

Intermediate Malignant Teratoma

Malignant Teratoma, Intermediate

Intermediate Immature Teratoma

Pyriform Sinus Cancer

Malignant Neoplasm Of Pyriform Fossa	Malignant Neoplasm Of The Pyriform Fossa
Malignant Tumor Of Pyriform Fossa

Supraglottis Neoplasm

Neoplasm Of Supraglottis

Supraglottic Tumor

Penile Disease

Penile Diseases

Trachea Carcinoma

Pancoast Tumor	Carcinoma Of The Trachea
Pancoast'S Tumor	Malignant Superior Sulcus Tumor
Malignant Superior Sulcus Tumour	Pancoast Tumour
Pancoast'S Syndrome	Pancoast'S Tumour
Pulmonary Sulcus Tumor	Pulmonary Sulcus Tumour
Superior Pulmonary Sulcus Syndrome	Pancoast Syndrome

Penile Benign Neoplasm

Neoplasm Of Penis	Penile Tumor
Cancer Of Penis	Carcinoma Of Penis
Malignant Neoplasm Of Penis, Unspecified	Malignant Neoplasm Of Penis, Part Unspecified
Malignant Tumour Of Penis	Penile Cancer
Primary Malignant Neoplasm Of Penis	Malignant Neoplasm Of Skin Of Penis Nos

Crigler-Najjar Syndrome, Type I

Crigler-Najjar Syndrome	Crigler-Najjar Syndrome Type 1
Bilirubin Udp Glucuronyl Transferase Deficiency	Crigler Najjar Syndrome
Crigler Najjar Syndrome, Type 1	Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency
Bilirubin-Ugt Deficiency	Hyperbilirubinemia, Crigler-Najjar Type I
Hblrcn1	Familial Nonhemolytic Unconjugated Hyperbilirubinemia
Hereditary Unconjugated Hyperbilirubinemia	Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency Type 1
Bilirubin-Ugt Deficiency Type 1	Crigler-Najjar Syndrome 1
CN1	Cn-I
Crigler-Najjar Syndrome Type I	Hereditary Unconjugated Hyperbilirubinaemia
Ugt Deficiency	Bilirubin Glucuronosyltransferase Deficiency
Crigler-Najjar Disease Or Syndrome	Deficiency Of Glucuronosyltransferase
Glucuronyl Transferase Deficiency	Glucuronyltransferase Deficiency
Udp Glucuronyl Transferase Deficiency	Cns - [Crigler-Najjar Syndrome]
Congenital Familial Nonhemolytic Jaundice

Tolosa-Hunt Syndrome

Painful Ophthalmoplegia	Tolosa Hunt Syndrome
Nonspecific Inflammation Of The Cavernous Sinus Or Superior Orbital Fissure	Ths
Ophthalmoplegia, Painful

Gastric Cancer

Stomach Cancer	Gastric Carcinoma
Stomach Carcinoma	Gastric Cancer, Somatic
Gastric Neoplasm	Carcinoma Of Stomach
Stomach Neoplasms	Malignant Neoplasm Of Stomach
Gastric Cancer Risk After H. Pylori Infection	Cancer Of The Stomach
Adult Stomach Cancer	Adult Stomach Carcinoma
GASC	Gastric Cancer Intestinal
Gastric Cancers	Gastric Carcinomas
Cancer, Gastric	Stomach Neoplasm
Malignant Neoplasm Of Body Of Stomach	Malignant Tumor Of Lesser Curve Of Stomach
Gastrocarcinoma Of Unspecified Site	Leather Bottle Stomach
Carcinoma Of Fundus Of Stomach	Cancer Of Fundus Of Stomach
Primary Malignant Neoplasm Of Body Of Stomach	Cancer Of Body Of Stomach
Primary Malignant Neoplasm Of Pyloric Antrum	Pyloric Antrum Cancer
Malignant Tumour Of Stomach

Gilbert Syndrome

Gilbert Disease	Gilbert'S Disease
Gilbert'S Syndrome	Cholemia, Familial
Familial Nonhemolytic Jaundice	Meulengracht Syndrome
Gilbert Syndrome, Susceptibility To	Hyperbilirubinemia, Gilbert Type
Hblrg	Hyperbilirubinemia, Arias Type
Hyperbilirubinemia I	Constitutional Hyperbilirubinemia
Gilbert-Meulengracht Syndrome	Hereditary Nonhemolytic Jaundice
Hyperbilirubinemia Arias Type	Hyperbilirubinemia Type 1
Constitutional Liver Dysfunction	Gilbert-Lereboullet Syndrome
Hyperbilirubinemia 1	Unconjugated Benign Bilirubinemia
GILBS	Gilberts Syndrome
Familial Nonhaemolytic Jaundice	Constitutional Hyperbilirubinaemia
Hereditary Nonhaemolytic Bilirubinaemia	Familial Nonhaemolytic Bilirubinaemia
Idiopathic Hyperbilirubinaemia	Icterus Intermittens Juvenilis
Chronic Intermittent Juvenile Jaundice	Low-Grade Chronic Hyperbilirubinaemia Syndrome
Benign Unconjugated Bilirubinaemia Syndrome	Hereditary Nonhaemolytic Jaundice
Idiopathic Unconjugated Hyperbilirubinaemia	Gilbert--Lereboullet Syndrome
Constitutional Hepatic Dysfunction	Meulengracht Icterus
Cholaemia Familiaris Simplex	Familial Cholaemia
Congenital Familial Cholaemia	Physiologic Cholaemia
Hyperbilirubinaemia Type 1	Gilbert Cholaemia

Bilirubin Metabolic Disorder

Hyperbilirubinemia	Hereditary Hyperbilirubinemia
Hyperbilirubinemia, Hereditary	Hyperbilirubinaemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02877	CNDP2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CNDP2	VGNC	VGNC:61009
Mus musculus	CNDP2	MGD	MGI:1913304
Canis familiaris	CNDP2	VGNC	VGNC:39392
Macaca mulatta	CNDP2	VGNC	VGNC:71337
Bos taurus	CNDP2	VGNC	VGNC:27494
Rattus norvegicus	CNDP2	RGD	RGD:1305827
Others	CNDP2	NCBI

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