SLC7A10 - solute carrier family 7 member 10 Gene

Homo sapiens

Also known as ASC1; asc-1; HASC-1

Gene ID: 56301 | Gene type: protein coding

About SLC7A10

Cytogenetic location: 19q13.11 Genomic coordinates (GRCh38): 19:33,208,664-33,225,850 (from NCBI)

This gene has 5 transcripts (splice variants), 301 orthologues and 12 paralogues. Broad expression in fat (RPKM 24.7), ovary (RPKM 10.1) and 14 other tissues.

Summary

SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral Amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]

SLC7A10 Products(1)

mRNA	Protein	Name
NM_019849.3	NP_062823.1	asc-type amino acid transporter 1

SLC7A10 Protein Structure

AA_permease_2

0
100
200
300
400
523 a.a.

Protein Preferred Names

Protein Names

asc-type amino acid transporter 1

solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10

Related Diseases

Diseases

Alias

Cystinuria

CSNU	Cystinuria Type B
Cystinuria Type A	Cystinuria, Type I, Formerly
Csnu1, Formerly	Cystinuria, Type Ii, Formerly
Cystinuria, Type Iii, Formerly	Csnu3, Formerly
Cystinuria, Type Non-I, Formerly	Cystinuria-Lysinuria
Cystinuria-Lysinuria Syndrome	Csnu1
Csnu3	Cystinuria 1
Cystinuria Type A/B	Cystinuria Type I
Cystinuria Type Ii	Cystinuria Type Iii
Cystinuria Type Non-I	Cystinuria, Type A/B
Cystinuria Type 1	Cystinuria - Lysinuria
Csnu - [Cystinuria]	Cystine Disease

Hyperekplexia

Hereditary Hyperekplexia	Kok Disease
Congenital Stiff Man Syndrome	Familial Startle Disease
Sthe	Stiff-Baby Syndrome
Hereditary Hyperexplexia	Startle Disease
Exaggerated Startle Reaction	Hyperexplexia Hereditary
Startle Disease, Familial	Startle Reaction, Exaggerated
Stiff-Man Syndrome, Congenital	Stiff-Person Syndrome, Congenital
Congenital Stiff-Man Syndrome	Congenital Stiff-Person Syndrome
Familial Hyperekplexia	Startle Syndrome
Stiff Baby Syndrome	Hyperekplexia, Hereditary
Stiff-Person Syndrome

Hypotonia-Cystinuria Syndrome

Cystinuria With Mitochondrial Disease	2p21 Microdeletion Syndrome
HCS	Homozygous 2p16 Deletion Syndrome, Formerly
2p21 Deletion Syndrome	Del(2)(P21)
Monosomy 2p21	Atypical Hypotonia-Cystinuria Syndrome
Atypical Hcs

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-120170	BMS-466442	Inhibitor	≥98.0%	Unkown
HY-RS13324	SLC7A10 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SLC7A10	MGD	MGI:1858261
Canis familiaris	SLC7A10	VGNC	VGNC:46471
Bos taurus	SLC7A10	VGNC	VGNC:34925
Felis catus	SLC7A10	VGNC	VGNC:65422
Rattus norvegicus	SLC7A10	RGD	RGD:621672
Macaca mulatta	SLC7A10	VGNC	VGNC:77627

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