2. Gene
  3. KIF13A - kinesin family member 13A Gene

KIF13A - kinesin family member 13A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RBKIN; bA500C11.2

Gene ID: 63971 | Gene type: protein coding

About KIF13A

Cytogenetic location: 6p22.3 Genomic coordinates (GRCh38): 6:17,759,126-17,987,635 (from NCBI)

This gene has 13 transcripts (splice variants), 204 orthologues and 41 paralogues. Ubiquitous expression in heart (RPKM 12.6), thyroid (RPKM 10.1) and 25 other tissues.

Summary

This gene encodes a member of the Kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

KIF13A Products(5)

mRNA Protein Name
NM_001105566.3 NP_001099036.1 kinesin-like protein KIF13A isoform b
NM_001105567.3 NP_001099037.1 kinesin-like protein KIF13A isoform c
NM_001105568.4 NP_001099038.1 kinesin-like protein KIF13A isoform d
NM_001243423.2 NP_001230352.1 kinesin-like protein KIF13A isoform e
NM_022113.6 NP_071396.4 kinesin-like protein KIF13A isoform a

KIF13A Protein Structure

Kinesin

Kinesin: Kinesin motor domain (11 - 352)

FHA

FHA: FHA domain (471 - 534)

KIF1B

KIF1B: Kinesin protein 1B (748 - 792)

DUF3694

DUF3694: Kinesin protein (1003 - 1083)

DUF3694

DUF3694: Kinesin protein (1171 - 1284)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1805 a.a.
Protein Preferred Names Protein Names

kinesin-like protein KIF13A

homolog of mouse KIF13A mannose-6-phosphate receptor transporter

Related Diseases

Diseases Alias
Hypomelanosis Of Ito

Incontinentia Pigmenti Achromians

Nevus Of Ito

Ipa

Ito Hypomelanosis

Ito

Pigmentation Disorders

HMI

Incontinentia Pigmenti, Type I, Formerly

Ip1, Formerly

Bloch-Siemans Syndrome

Incontinentia Pigmenti Achromians Syndrome

Ito'S Nevus

Incontinentia Pigmenti Type 1

Nevi Of Ito

Nevus Fuscocaeruleus Acromiodeltoideus

Bloch Sulzberger Syndrome

Skin Pigmentation Disorder
Hermansky-Pudlak Syndrome

Hps

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

Hermanski-Pudlak Syndrome

Hermansky Pudlak Syndrome

Platelet Storage Pool Deficiency
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07259 KIF13A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KIF13A VGNC VGNC:42381
Mus musculus KIF13A MGD MGI:1098264
Bos taurus KIF13A VGNC VGNC:54226
Felis catus KIF13A VGNC VGNC:63102
Rattus norvegicus KIF13A RGD RGD:1307825
Macaca mulatta KIF13A VGNC VGNC:73830