GAL3ST2 - galactose-3-O-sulfotransferase 2 Gene

Also Known as GP3ST; GAL3ST-2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64090

Summary

This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the hydroxyl at C-3 of nonreducing beta-galactosyl residues, and it can act on both type 1 and type 2 (Galbeta 1-3/1-4GlcNAc-R) Oligosaccharides with similar efficiencies, and on core 1 glycans. This enzyme has been implicated in tumor metastasis processes. This gene is different from the GAL3ST3 gene located on chromosome 11, which has also been referred to as GAL3ST2 and encodes a related enzyme with distinct tissue distribution and substrate specificities, compared to galactose-3-O-sulfotransferase 2. [provided by RefSeq, Jul 2008]
Restricted expression toward colon (RPKM 8.9).

GAL3ST2 Products (1)

mRNA Protein Name
NG_046977.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables sulfotransferase activity IDA
IDA: Inferred from direct assay
11029462 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GAL3ST2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GAL3ST2 Q9H3Q3 MTUS2 Homo sapiens Q5JR59
Validated Y2H
25416956
Intra
GAL3ST2 Q9H3Q3 MTUS2 Homo sapiens Q5JR59
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS29497 GAL3ST2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-E70169 Galactose-3-O-sulfotransferase 2 / Unkown