32 Results for "

64090

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "64090" in MCE Product Catalog:

Cat. No.: HY-112624B
CAS No.: 9004-54-0
Synonyms: Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.
Cat. No.: HY-106011
CAS No.: 913541-47-6
Purity:  99.71%
SLX-4090 is an orally active enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 8.0 nM. SLX-4090 can be used for the research of dyslipidemia .
Cat. No.: HY-112624E
CAS No.: 9004-54-0
Synonyms: Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)
Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
Cat. No.: HY-103671
CAS No.: 1853164-83-6
Purity:  99.47%
Target:  

Glutaminase

Research Areas:  

Inflammation/Immunology Cancer

IPN-60090 is an orally active and highly selective inhibitor of glutaminase 1 (GLS1; IC50=31 nM), with no activity observed against GLS-2. IPN-60090 exhibits excellent physicochemical and pharmacokinetic properties in vivo. IPN-60090 can be used for solid tumors research, such as lung and ovarian cancers .
Cat. No.: HY-103671A
CAS No.: 2102101-72-2
Purity:  99.68%
Target:  

Glutaminase

Research Areas:  

Inflammation/Immunology Cancer

IPN-60090 dihydrochloride is an orally active and highly selective inhibitor of glutaminase 1 (GLS1; IC50=31 nM), with no activity observed against GLS-2. IPN-60090 dihydrochloride exhibits excellent physicochemical and pharmacokinetic properties in vivo. IPN-60090 dihydrochloride can be used for solid tumors research, such as lung and ovarian cancers .
Cat. No.: HY-147251
CAS No.: 127697-58-9
Purity:  99.25%
Target:  

Drug Derivative

Research Areas:  

Others

SRI 6409-94 is an orally active Ro 13-6298 analogue that is teratogenic. SRI 6409-94 serves as a molecular tool to study the effect of the three-dimensional configuration of retinol on teratogenic activity .
Cat. No.: HY-P991281

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

REGN6490 is a humanized monoclonal anti-IL1RL2/IL-36R antibody. REGN6490 can be used in research related to pustular psoriasis .
Cat. No.: HY-Y0850AGL2
CAS No.: 9002-89-5
Synonyms: PVA, MW 64000 (GMP Like)
Polyvinyl alcohol, MW 64000 (GMP Like) (PVA, MW 64000 (GMP Like)) is the GMP Like class Polyvinyl alcohol, MW 64000 that can be used as pharmaceutical excipients.
Cat. No.: HY-R01865
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-6090 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
Cat. No.: HY-R03407
Target:  

MicroRNA

Research Areas:  

Cancer

mmu-miR-6400 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
Cat. No.: HY-103671AR
CAS No.: 2102101-72-2
IPN60090 dihydrochloride (Standard) is the analytical standard of IPN60090 dihydrochloride (HY-103671A). This product is intended for research and analytical applications. IPN-60090 dihydrochloride is an orally active and highly selective inhibitor of glutaminase 1 (GLS1; IC50=31 nM), with no activity observed against GLS-2. IPN-60090 dihydrochloride exhibits excellent physicochemical and pharmacokinetic properties in vivo. IPN-60090 dihydrochloride can be used for solid tumors research, such as lung and ovarian cancers .
Cat. No.: HY-103671R
CAS No.: 1853164-83-6
IPN60090 (Standard) is the analytical standard of IPN60090 (HY-103671). This product is intended for research and analytical applications. IPN-60090 is an orally active and highly selective inhibitor of glutaminase 1 (GLS1; IC50=31 nM), with no activity observed against GLS-2. IPN-60090 exhibits excellent physicochemical and pharmacokinetic properties in vivo. IPN-60090 can be used for solid tumors research, such as lung and ovarian cancers .
Cat. No.: HY-106011R
CAS No.: 913541-47-6
SLX-4090 (Standard) is the analytical standard of SLX-4090 (HY-106011). This product is intended for research and analytical applications. SLX-4090 is an orally active enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 8.0 nM. SLX-4090 can be used for the research of dyslipidemia .
Cat. No.: HY-19591
CAS No.: 19888-56-3
Synonyms: L-6400
Fluazacort (L-6400), oxazolino corticosteroid, is a Glucocorticoid Receptor (GR) modulator. Fluazacort can be used for the research of inflammation, immunology and metabolic disease .
Cat. No.: HY-R01865A
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-6090 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Cat. No.: HY-R03407A
Target:  

MicroRNA

Research Areas:  

Cancer

mmu-miR-6400 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Cat. No.: HY-R03416
Target:  

MicroRNA

Research Areas:  

Cancer

mmu-miR-6409 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
Cat. No.: HY-R03416A
Target:  

MicroRNA

Research Areas:  

Cancer

mmu-miR-6409 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Cat. No.: HY-RI01865
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-6090 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
Cat. No.: HY-RI01865A
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-6090 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.