19888-56-3
19888-56-3
Chemical Structure
Fluazacort
Synonym(s): L-6400
- CAS 番号: 19888-56-3
- Formula:C25H30FNO6
- Molecular Weight:459.51
IUPAC Name: 2-(6b-fluoro-7-hydroxy-6a,8a,10-trimethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl)-2-oxoethyl acetate
InChIKey: BYZCJOHDXLROEC-UHFFFAOYSA-N
SMILES: O=C1C=CC2(C)C(CCC3C4CC5OC(C)=NC5(C4(CC(C32F)O)C)C(COC(C)=O)=O)=C1
Biological Activity: Fluazacort (L-6400), oxazolino corticosteroid, is a Glucocorticoid Receptor (GR) modulator. Fluazacort can be used for the research of inflammation, immunology and metabolic disease[1].
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Fluazacort | Fluazacort (L-6400), oxazolino corticosteroid, is a Glucocorticoid Receptor (GR) modulator. Fluazacort can be used for the research of inflammation, immunology and metabolic disease. | |||||||||||||||||||||
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References
- [1]. Lewis JD, et al. Percutaneous absorption of 14C-9alpha-fluoro-11beta,21-dihydroxy-3,20-dioxopregna-1,4-dieno (17alpha,16alpha-d)-2'-methyloxazolidine-21-acetate (L 6400) in rats, pigs and humans. Comparison with 3H-triamcinolone acetonide. Arzneimittelforschung. 1975 Oct;25(10):1646-50. [Content Brief]
Keywords
