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No matches for "

64763

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

26

Inhibitors & Agonists

2

Peptides

1

Isotope-Labeled Compounds

5

Antibodies

16

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-11018
    Risperidone
    5+ Cited Publications

    R 64 766

    		 5-HT Receptor Dopamine Receptor P-glycoprotein Neurological Disease
    Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.
    Risperidone
  • HY-P1934
    Cyclo(Phe-Pro)
    5+ Cited Publications

    Cyclo(phenylalanylprolyl); A-64863

    		 HCV Bacterial Antibiotic Reactive Oxygen Species (ROS) Infection
    Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that specifically interacts with RIG-I, inhibiting RIG-I polyubiquitination, suppressing IRF-3 activation, and reducing type I interferon production. Cyclo(Phe-Pro) enhances susceptibility to HCV and influenza virus and also alleviates plant aluminum toxicity stress. The mechanism of Cyclo(Phe-Pro) involves the regulation of host immune signaling pathways, bacterial virulence gene expression, and plant antioxidant systems, making it a promising candidate for research in viral infections, bacterial virulence regulation, and agricultural stress resistance .
    Cyclo(Phe-Pro)
  • HY-145607
    Zagociguat

    CY-6463; IW-6463

    		 Guanylate Cyclase Interleukin Related Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Zagociguat (CY-6463) is an orally active and BBB-permeable soluble guanylate cyclase (sGC) stimulator. Zagociguat can increase cGMP levels, regulate blood pressure, improve neuronal function, reduce inflammatory responses, and exert neuroprotective and cognitive-improving effects. Zagociguat can be used in the research of neurodegenerative diseases .
    Zagociguat
  • HY-116568
    Prothioconazole

    JAU-6476

    		 Fungal Cytochrome P450 Microtubule/Tubulin Mitochondrial Metabolism DNA/RNA Synthesis Apoptosis Fatty Acid Synthase (FASN) Infection Metabolic Disease Endocrinology
    Prothioconazole is an orally active broad-spectrum fungicide. Prothioconazole weakly inhibits CaCYP51 activity in Candida albicans, with an apparent IC50 of approximately 120 μM. Prothioconazole disrupts Microtubule stability by reducing the acetylation level of α-tubulin. Prothioconazole induces Mitochondrial dysfunction, oxidative stress, DNA damage, and Apoptosis. Prothioconazole accumulates 14-methylated sterols and depletes ergosterol in cells, culture media, plants, and animals. Prothioconazole interferes with pyruvate metabolism and glycolysis/gluconeogenesis processes in mouse liver, downregulates Fasn mRNA expression, and induces hepatotoxicity and renal metabolic disorders. Prothioconazole reduces the fertility of female mice. Prothioconazole inhibits body weight gain and increases liver/kidney indices in mice. Prothioconazole can be used in studies related to candidiasis .
    Prothioconazole
  • HY-11018B
    Risperidone mesylate

    R 64 766 mesylate

    		 5-HT Receptor Dopamine Receptor P-glycoprotein Neurological Disease
    Risperidone mesylate(R 64 766 mesylate) is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.
    Risperidone mesylate
  • HY-11018A
    Risperidone hydrochloride

    R 64 766 hydrochloride

    		 5-HT Receptor Dopamine Receptor P-glycoprotein Neurological Disease
    Risperidone hydrochloride (R 64 766 hydrochloride) 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.
    Risperidone hydrochloride
  • HY-P10246
    Hemoglobin (64-76)

    		MHC Inflammation/Immunology
    Hemoglobin 64-76 is a T cell inducing determinant, that binds to two different MHC class II molecules in distinct registers and lengths .
    Hemoglobin (64-76)
  • HY-116568R
    Prothioconazole (Standard)

    JAU-6476 (Standard)

    		 Fungal Cytochrome P450 Reference Standards Infection
    Prothioconazole (Standard) is the analytical standard of Prothioconazole. This product is intended for research and analytical applications. Prothioconazole is a triazolinthione fungicide. Prothioconazole is a CYP51 inhibitor .
    Prothioconazole (Standard)
  • HY-R01384
    hsa-miR-4763-3p mimic

    		MicroRNA Cancer
    hsa-miR-4763-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-4763-3p mimic
    hsa-miR-4763-3p mimic
  • HY-R02084A
    hsa-miR-6763-3p agomir

    		MicroRNA Cancer
    hsa-miR-6763-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6763-3p agomir
    hsa-miR-6763-3p agomir
  • HY-R01385
    hsa-miR-4763-5p mimic

    		MicroRNA Cancer
    hsa-miR-4763-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-4763-5p mimic
    hsa-miR-4763-5p mimic
  • HY-RI02085A
    hsa-miR-6763-5p antagomir

    		MicroRNA Cancer
    hsa-miR-6763-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6763-5p antagomir
    hsa-miR-6763-5p antagomir
  • HY-RI01385
    hsa-miR-4763-5p inhibitor

    		MicroRNA Cancer
    hsa-miR-4763-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-4763-5p inhibitor
    hsa-miR-4763-5p inhibitor
  • HY-11018R
    Risperidone (Standard)

    R 64 766 (Standard)

    		 Dopamine Receptor 5-HT Receptor P-glycoprotein Reference Standards Neurological Disease
    Risperidone (Standard) is the analytical standard of Risperidone. This product is intended for research and analytical applications. Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.
    Risperidone (Standard)
  • HY-116568S
    Prothioconazole-d4

    JAU-6476-d4

    		 Isotope-Labeled Compounds Fungal Cytochrome P450 Infection
    Prothioconazole-d4 (JAU-6476-d4) is the deuterium labeled Prothioconazole (HY-116568). Prothioconazole is a triazolinthione fungicide. Prothioconazole is a CYP51 inhibitor .
    Prothioconazole-d4
  • HY-RI02084
    hsa-miR-6763-3p inhibitor

    		MicroRNA Cancer
    hsa-miR-6763-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-6763-3p inhibitor
    hsa-miR-6763-3p inhibitor
  • HY-R01385A
    hsa-miR-4763-5p agomir

    		MicroRNA Cancer
    hsa-miR-4763-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-4763-5p agomir
    hsa-miR-4763-5p agomir
  • HY-R02084
    hsa-miR-6763-3p mimic

    		MicroRNA Cancer
    hsa-miR-6763-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-6763-3p mimic
    hsa-miR-6763-3p mimic
  • HY-R02085
    hsa-miR-6763-5p mimic

    		MicroRNA Cancer
    hsa-miR-6763-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-6763-5p mimic
    hsa-miR-6763-5p mimic
  • HY-R01384A
    hsa-miR-4763-3p agomir

    		MicroRNA Cancer
    hsa-miR-4763-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-4763-3p agomir
    hsa-miR-4763-3p agomir
  • HY-RI02084A
    hsa-miR-6763-3p antagomir

    		MicroRNA Cancer
    hsa-miR-6763-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6763-3p antagomir
    hsa-miR-6763-3p antagomir
  • HY-RI01385A
    hsa-miR-4763-5p antagomir

    		MicroRNA Cancer
    hsa-miR-4763-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-4763-5p antagomir
    hsa-miR-4763-5p antagomir
  • HY-RI02085
    hsa-miR-6763-5p inhibitor

    		MicroRNA Cancer
    hsa-miR-6763-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-6763-5p inhibitor
    hsa-miR-6763-5p inhibitor
  • HY-RI01384
    hsa-miR-4763-3p inhibitor

    		MicroRNA Cancer
    hsa-miR-4763-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-4763-3p inhibitor
    hsa-miR-4763-3p inhibitor
  • HY-RI01384A
    hsa-miR-4763-3p antagomir

    		MicroRNA Cancer
    hsa-miR-4763-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-4763-3p antagomir
    hsa-miR-4763-3p antagomir
  • HY-R02085A
    hsa-miR-6763-5p agomir

    		MicroRNA Cancer
    hsa-miR-6763-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6763-5p agomir
    hsa-miR-6763-5p agomir

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