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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
64976
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "64976" in MCE Product Catalog:
14
14 Cited Publications
Target:
Research Areas:
Go6976 is a Protein Kinase C (PKC) inhibitor, with an IC50 of 20 nM.
1
1 Cited Publications
Cat. No.: HY-P86804
Synonyms: 4930549J05Rik antibody;
A430104F18Rik antibody;
AW552088 antibody;
Cd247 antibody;
CD3 antibody;
CD3 delta antibody;
CD3 epsilon antibody;
CD3 eta antibody;
CD3 gamma antibody;
CD3 zeta antibody;
CD3H antibody;
CD3Q antibody;
CD3Z antibody;
CD3zeta antibody;
Ctg3 antibody;
FLJ17620 antibody;
FLJ17664 antibody;
FLJ18683 antibody;
FLJ79544 antibody
FLJ94613 antibody;
IMD19 antibody;
Leu-4 antibody;
MGC138597 antibody;
OKT3, delta chain antibody;
OTTHUMP00000032544 antibody;
T cell receptor antibody;
T3 antibody;
T3d antibody;
T3e antibody;
T3g antibody;
T3z antibody;
TCRE antibody;
TCRk antibody;
Tcrz antibody;
TCRzeta antibody
Target:
Research Areas:
FPL64176, a nondihydropyridine compound, is a potent agonist of L-type Ca 2+ channels with an EC50 value of 16 nM .
Synonyms: JAU-6476
Target:
Fungal Cytochrome P450 Microtubule/Tubulin Mitochondrial Metabolism DNA/RNA Synthesis Apoptosis Fatty Acid Synthase (FASN)
Research Areas:
Prothioconazole is an orally active broad-spectrum fungicide. Prothioconazole weakly inhibits CaCYP51 activity in Candida albicans, with an apparent IC50 of approximately 120 μM. Prothioconazole disrupts Microtubule stability by reducing the acetylation level of α-tubulin. Prothioconazole induces Mitochondrial dysfunction, oxidative stress, DNA damage, and Apoptosis. Prothioconazole accumulates 14-methylated sterols and depletes ergosterol in cells, culture media, plants, and animals. Prothioconazole interferes with pyruvate metabolism and glycolysis/gluconeogenesis processes in mouse liver, downregulates Fasn mRNA expression, and induces hepatotoxicity and renal metabolic disorders. Prothioconazole reduces the fertility of female mice. Prothioconazole inhibits body weight gain and increases liver/kidney indices in mice. Prothioconazole can be used in studies related to candidiasis .
Cat. No.: HY-126327A
Purity: ≥98.0%
Target:
Research Areas:
Cat. No.: HY-126327
CAS No.: 2920299-34-7
Target:
Research Areas:
Cat. No.: HY-103307R
CAS No.: 120934-96-5
Target:
Research Areas:
FPL64176 (Standard) is the analytical standard of FPL64176. This product is intended for research and analytical applications. FPL64176, a nondihydropyridine compound, is a potent agonist of L-type Ca2+ channels with an EC50 value of 16 nM .
Cat. No.: HY-P10246
CAS No.: 139644-18-1
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Research Areas:
Cat. No.: HY-100159
CAS No.: 104454-71-9
Synonyms: MLV-6976; NC-1200
Target:
Research Areas:
Ipenoxazone is a potent and centrally acting muscle relaxant.
Cat. No.: HY-100159A
CAS No.: 118635-68-0
Synonyms: MLV-6976 hydrochloride; NC-1200 hydrochloride
Target:
Research Areas:
Ipenoxazone (MLV-6976) hydrochloride is a potent and centrally acting muscle relaxant.
Cat. No.: HY-116568R
CAS No.: 178928-70-6
Synonyms: JAU-6476 (Standard)
Target:
Research Areas:
Prothioconazole (Standard) is the analytical standard of Prothioconazole. This product is intended for research and analytical applications. Prothioconazole is a triazolinthione fungicide. Prothioconazole is a CYP51 inhibitor .
Cat. No.: HY-RI03682A
mmu-miR-6976-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Cat. No.: HY-116568S
Synonyms: JAU-6476-d4
Cat. No.: HY-R03682A
mmu-miR-6976-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Cat. No.: HY-R03683A
mmu-miR-6976-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Cat. No.: HY-RI03682
mmu-miR-6976-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
Cat. No.: HY-RI03683
mmu-miR-6976-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
Cat. No.: HY-RI03683A
mmu-miR-6976-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
