2. Gene
  3. Stx12 - syntaxin 12 Gene

Stx12 - syntaxin 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 65033 | Gene type: protein coding

About Stx12

Summary

Predicted to enable SNAP receptor activity and SNARE binding activity. Involved in synaptic vesicle to endosome fusion. Located in postsynaptic recycling endosome and synaptic vesicle. Is integral component of synaptic vesicle membrane. Orthologous to human STX12 (syntaxin 12). [provided by Alliance of Genome Resources, Apr 2022]

Stx12 Products(1)

mRNA Protein Name
NM_022939.2 NP_075228.2 syntaxin-12
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12070131 RGD
Biological Process GO Annotation Evidence Reference Source
involved in endocytic recycling IDA
IDA: Inferred from direct assay
30962439 RGD
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
15448273 RGD
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
15448273 RGD
involved in synaptic vesicle to endosome fusion IDA
IDA: Inferred from direct assay
17004320 RGD
involved in synaptic vesicle to endosome fusion IMP
IMP: Inferred from mutant phenotype
17004320 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17145503 RGD
is active in postsynaptic recycling endosome membrane IDA
IDA: Inferred from direct assay
17145503 RGD
located in recycling endosome IDA
IDA: Inferred from direct assay
30962439 RGD
is active in synaptic vesicle membrane EXP
EXP: Inferred from Experiment
17110340 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
17004320 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

syntaxin-12

Syn13

syntaxin-13

Stx12 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Stx12 G3V7P1 Vamp1 Rattus norvegicus Q63666
Anti Bait CoIP
17717530
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13976 STX12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stx12 NCBI NCBI:23673