SCN1A - sodium voltage-gated channel alpha subunit 1 Gene
Species: Macaca mulatta
Gene Type: protein coding
Gene ID: 704086
About SCN1A
Primary_assembly 12: 53,133,881-53,222,776 reverse strand.Mmul_10:CM014347.1
This gene has 1 transcript (splice variant), 140 orthologues and 25 paralogues.
SCN1A Products (14)
| mRNA | Protein | Name |
|---|---|---|
| XM_028830794.1 | XP_028686627.1 | sodium channel protein type 1 subunit alpha isoform X1 |
| XM_028830798.1 | XP_028686631.1 | sodium channel protein type 1 subunit alpha isoform X3 |
| XM_001100928.4 | XP_001100928.1 | sodium channel protein type 1 subunit alpha isoform X5 |
| XM_015110268.2 | XP_014965754.1 | sodium channel protein type 1 subunit alpha isoform X4 |
| XM_001101023.4 | XP_001101023.1 | sodium channel protein type 1 subunit alpha isoform X1 |
| XM_028830795.1 | XP_028686628.1 | sodium channel protein type 1 subunit alpha isoform X1 |
| XM_028830797.1 | XP_028686630.1 | sodium channel protein type 1 subunit alpha isoform X3 |
| XM_028830803.1 | XP_028686636.1 | sodium channel protein type 1 subunit alpha isoform X5 |
| XM_028830796.1 | XP_028686629.1 | sodium channel protein type 1 subunit alpha isoform X2 |
| XM_028830800.1 | XP_028686633.1 | sodium channel protein type 1 subunit alpha isoform X3 |
| XM_028830801.1 | XP_028686634.1 | sodium channel protein type 1 subunit alpha isoform X4 |
| XM_001101115.4 | XP_001101115.1 | sodium channel protein type 1 subunit alpha isoform X3 |
| XM_028830802.1 | XP_028686635.1 | sodium channel protein type 1 subunit alpha isoform X5 |
| XM_028830804.1 | XP_028686637.1 | sodium channel protein type 1 subunit alpha isoform X6 |
SCN1A Protein Structure
Ion_trans
Ion_trans: pfam00520 (126 - 432)
Na_trans_cytopl
Na_trans_cytopl: pfam11933 (554 - 717)
Ion_trans
Ion_trans: pfam00520 (766 - 979)
Na_trans_assoc
Na_trans_assoc: pfam06512 (1005 - 1212)
Ion_trans
Ion_trans: pfam00520 (1216 - 1491)
Na_channel_gate
Na_channel_gate: cd13433 (1483 - 1535)
Ion_trans
Ion_trans: pfam00520 (1539 - 1795)
- 0
- 400
- 800
- 1200
- 1600
- 2008 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sodium channel protein type 1 subunit alpha |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-148410A | Zorevunersen sodium | Activator | 99.27% | Phase 3 |
| HY-148410 | Zorevunersen | Activator | 98.50% | Phase 3 |
Pre-clinical Phase
Bioactive Molecules
(6)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-125928 | AA43279 | Inhibitor | 99.80% | Unkown |
| HY-148410C | Zorevunensen negative control | Activator | 99.28% | Unkown |
| HY-181575 | TPH2 agonist-1 | Inhibitor | / | Unkown |
| HY-RS12525 | SCN1A Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS12526 | Scn1a Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS12527 | SCN1A Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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