2. Gene
  3. SCN1A - sodium voltage-gated channel alpha subunit 1 Gene

SCN1A - sodium voltage-gated channel alpha subunit 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta
Gene ID: 704086 | Gene type: protein coding

About SCN1A

Primary_assembly 12: 53,133,881-53,222,776 reverse strand.Mmul_10:CM014347.1

This gene has 1 transcript (splice variant), 140 orthologues and 25 paralogues.

SCN1A Products(14)

mRNA Protein Name
XM_028830794.1 XP_028686627.1 sodium channel protein type 1 subunit alpha isoform X1
XM_028830798.1 XP_028686631.1 sodium channel protein type 1 subunit alpha isoform X3
XM_001100928.4 XP_001100928.1 sodium channel protein type 1 subunit alpha isoform X5
XM_015110268.2 XP_014965754.1 sodium channel protein type 1 subunit alpha isoform X4
XM_001101023.4 XP_001101023.1 sodium channel protein type 1 subunit alpha isoform X1
XM_028830795.1 XP_028686628.1 sodium channel protein type 1 subunit alpha isoform X1
XM_028830797.1 XP_028686630.1 sodium channel protein type 1 subunit alpha isoform X3
XM_028830803.1 XP_028686636.1 sodium channel protein type 1 subunit alpha isoform X5
XM_028830796.1 XP_028686629.1 sodium channel protein type 1 subunit alpha isoform X2
XM_028830800.1 XP_028686633.1 sodium channel protein type 1 subunit alpha isoform X3
XM_028830801.1 XP_028686634.1 sodium channel protein type 1 subunit alpha isoform X4
XM_001101115.4 XP_001101115.1 sodium channel protein type 1 subunit alpha isoform X3
XM_028830802.1 XP_028686635.1 sodium channel protein type 1 subunit alpha isoform X5
XM_028830804.1 XP_028686637.1 sodium channel protein type 1 subunit alpha isoform X6

SCN1A Protein Structure

Ion_trans

Ion_trans: pfam00520 (126 - 432)

Na_trans_cytopl

Na_trans_cytopl: pfam11933 (554 - 717)

Ion_trans

Ion_trans: pfam00520 (766 - 979)

Na_trans_assoc

Na_trans_assoc: pfam06512 (1005 - 1212)

Ion_trans

Ion_trans: pfam00520 (1216 - 1491)

Na_channel_gate

Na_channel_gate: cd13433 (1483 - 1535)

Ion_trans

Ion_trans: pfam00520 (1539 - 1795)

  • 0
  • 400
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  • 1200
  • 1600
  • 2008 a.a.
Protein Preferred Names Protein Names

sodium channel protein type 1 subunit alpha

sodium channel, voltage-gated, type I, alpha subunit

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-148410A Zorevunersen sodium Activator 99.27% Phase 3
HY-148410 Zorevunersen Activator / Phase 3
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-125928 AA43279 Inhibitor 99.80% Unkown
HY-148410C Zorevunensen negative control Activator 99.28% Unkown
HY-181575 TPH2 agonist-1 Inhibitor / Unkown
HY-RS12525 SCN1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12526 Scn1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12527 SCN1A Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SCN1A NCBI NCBI:6323