2. Gene
  3. METTL22 - methyltransferase 22, Kin17 lysine Gene

METTL22 - methyltransferase 22, Kin17 lysine Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as C16orf68

Gene ID: 79091 | Gene type: protein coding

About METTL22

Cytogenetic location: 16p13.2 Genomic coordinates (GRCh38): 16:8,621,698-8,667,274 (from NCBI)

This gene has 18 transcripts (splice variants) and 187 orthologues. Ubiquitous expression in testis (RPKM 2.7), endometrium (RPKM 1.3) and 25 other tissues.

Summary

This gene encodes a member of the non-histone lysine methyltransferases. It interacts with its substrate, Kin17, which is involved in DNA repair and replication and mRNA processing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

METTL22 Products(1)

mRNA Protein Name
NM_024109.4 NP_077014.4 methyltransferase-like protein 22

METTL22 Protein Structure

Methyltransf_16

Methyltransf_16: Lysine methyltransferase (179 - 337)

  • 0
  • 100
  • 200
  • 300
  • 404 a.a.
Protein Preferred Names Protein Names

methyltransferase-like protein 22

LP8272

Related Diseases

Diseases Alias
Esophageal Atresia/Tracheoesophageal Fistula

Esophageal Atresia And/Or Tracheoesophageal Fistula

Tracheoesophageal Fistula With Or Without Esohageal Atresia

Esophageal Atresia / Tracheoesophageal Fistula

Ea/Tef

Esophageal Atresia With Tracheoesophageal Fistula

Esophageal Atresia With Or Without Tracheoesophageal Fistula
Histidinemia

Histidine Ammonia-Lyase Deficiency

Hal Deficiency

Histidase Deficiency

His Deficiency

Histidinuria

Hyperhistidinemia

HISTID

Histidinuria Renal Tubular Defect
Histidine Metabolism Disease

Disturbances Of Histidine Metabolism

Disorder Of Histidine Metabolism

Disturbance Of Histidine Metabolism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08361 METTL22 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus METTL22 VGNC VGNC:63462
Canis familiaris METTL22 VGNC VGNC:43175
Rattus norvegicus METTL22 RGD RGD:1311433
Bos taurus METTL22 VGNC VGNC:31408
Mus musculus METTL22 MGD MGI:2384301
Macaca mulatta METTL22 VGNC VGNC:74602