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79176

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10

Inhibitors & Agonists

1

Recombinant Proteins

8

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-109101
    Risdiplam
    5+ Cited Publications

    RG7916; RO7034067

    		 DNA/RNA Synthesis Neurological Disease
    Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels .
    Risdiplam
  • HY-162401
    AZ7976

    		RXFP Receptor Cardiovascular Disease
    AZ7976 (Compound 42) is a highly selective agonist for the Relaxin Family Peptide Receptor 1 (RXFP1) (pEC50 > 10.5). AZ7976 enhances RXFP1's cAMP signaling through an allosteric mechanism, thereby physiologically increasing heart rate. AZ7976 can be used in the field of cardiovascular disease research .
    AZ7976
  • HY-15005A
    PSI-7976

    		HCV Infection
    PSI-7976 is the isomer of PSI-7977. PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
    PSI-7976
  • HY-109101R
    Risdiplam (Standard)

    RG7916 (Standard); RO7034067 (Standard)

    		 Reference Standards DNA/RNA Synthesis Neurological Disease
    Risdiplam (Standard) is the analytical standard of Risdiplam. This product is intended for research and analytical applications. Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels .
    Risdiplam (Standard)
  • HY-129685
    M79175

    		Aldose Reductase Metabolic Disease
    M79175 is an aldose reductase inhibitor that can be used in the study of early diabetic retinopathy .
    M79175
  • HY-116164
    A-79175

    		Lipoxygenase Inflammation/Immunology
    A-79175 is a potent 5-lipoxygenase inhibitor that inhibits leukotriene formation. A-79175 is promising for research of various allergic and inflammatory diseases including asthma, allergic rhinitis, rheumatoid arthritis and inflammatory bowel disease .
    A-79175
  • HY-R02440
    hsa-miR-7976 mimic

    		MicroRNA Cancer
    hsa-miR-7976 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-7976 mimic
    hsa-miR-7976 mimic
  • HY-R02440A
    hsa-miR-7976 agomir

    		MicroRNA Cancer
    hsa-miR-7976 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-7976 agomir
    hsa-miR-7976 agomir
  • HY-RI02440A
    hsa-miR-7976 antagomir

    		MicroRNA Cancer
    hsa-miR-7976 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-7976 antagomir
    hsa-miR-7976 antagomir
  • HY-RI02440
    hsa-miR-7976 inhibitor

    		MicroRNA Cancer
    hsa-miR-7976 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-7976 inhibitor
    hsa-miR-7976 inhibitor

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