ALDOB Antibody (YA7976)

Cat. No.: HY-P88292: Data Sheet User Guide for Antibodies
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ALDOB Antibody (YA7976) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to ALDOB.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ALDOB Antibody (YA7976) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to ALDOB.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 39.3 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P05062

Immunogen

Full length human recombinant protein of human ALDOB produced in HEK293 cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde (PubMed:10970798, PubMed:12205126, PubMed:20848650). Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check (PubMed:35122041)

Subcellular Localization：Cytoplasm, cytosol,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite

Isoforms & Post-Translational Modification：P05062: 364 amino acids, molecular weight 39473 Da.

Subunit：Homotetramer

Synonyms

ALDB; ALDO2

Documentation

User Guide for Antibodies (1077 KB)