ALDOB Antibody (YA7976)
(Synonyms: ALDB; ALDO2)ALDOB Antibody (YA7976) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to ALDOB.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IHC-P, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:1000-4000 | 1:150-500 | 1:100 |
Product Details
ALDOB Antibody (YA7976) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to ALDOB.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 39.3 kDa
Full length human recombinant protein of human ALDOB produced in HEK293 cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ALDOB catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde. Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check[1][2][3][4].
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Subcellular Localization
Cytoplasm, cytosol,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite
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Isoforms & Post-Translational Modification
P05062: 364 amino acids, molecular weight 39473 Da.
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Subunit
Homotetramer
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SwissProt ID
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Synonyms
ALDB; ALDO2
Documentation
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