ROGDI - rogdi atypical leucine zipper Gene

Also Known as KTZS; RAV2; ROGD1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 79641

About ROGDI

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:4,796,968-4,802,633 (from NCBI)

This gene has 16 transcripts (splice variants), 193 orthologues and is associated with 3 phenotypes. Ubiquitous expression in brain (RPKM 26.0), bone marrow (RPKM 23.4) and 25 other tissues.

Summary

This gene encodes a protein of unknown function. Loss-of-function mutation in this gene cause Kohlschutter-Tonz syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

ROGDI Products (1)

mRNA	Protein	Name
NM_024589.3	NP_078865.1	protein rogdi homolog

ROGDI Protein Structure

Rogdi_lz

0
100
200
287 a.a.

Protein Preferred Names	Protein Names
protein rogdi homolog	leucine zipper domain protein

ROGDI Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ROGDI	Q9GZN7	CEP63	Homo sapiens	Q96MT8-3	Y2H Prey Pooling	32296183
Intra	ROGDI	Q9GZN7	CEP63	Homo sapiens	Q96MT8-3	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Kohlschutter-Tonz Syndrome	Amelocerebrohypohidrotic Syndrome KTZS Epilepsy And Yellow Teeth Kohlschutter Tonz Syndrome Kohlschutter Syndrome Epilepsy Dementia Amelogenesis Imperfecta Epilepsy-Dementia-Amelogenesis Imperfecta Syndrome Epilepsy, Dementia, And Amelogenesis Imperfecta Kohlschutter'S Syndrome Kohlschütter-Tönz Syndrome Kohlschuetter-Toenz Syndrome Presenile Dementia Dementia
Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 2	SEMDJL2 Spondyloepimetaphyseal Dysplasia With Joint Laxity, Leptodactylic Type Spondyloepimetaphyseal Dysplasia With Multiple Dislocations, Hall Type Spondyloepimetaphyseal Dysplasia With Joint Laxity Type 2 Spondyloepimetaphyseal Dysplasia With Multiple Dislocations Hall Type Spondyloepimetaphyseal Dysplasia With Joint Laxity, Hall Type Semd-Md Spondyloepimetaphyseal Dysplasia With Joint Laxicity, Hall Type Spondyloepimetaphyseal Dysplasia With Joint Laxity, 2 Lepto-Semdjl Spondyloepimetaphyseal Dysplasia With Joint Laxity Hall Type Spondyloepimetaphyseal Dysplasia With Joint Laxity Leptodactylic Type Spondyloepimetaphyseal Dysplasia With Multiple Dislocations
Complex Partial Epilepsy	Epilepsy, Complex Partial Complex Partial Epileptic Seizure Epilepsy, Psychomotor Psychomotor Epilepsy
Immunodeficiency 9	Immune Dysfunction With T-Cell Inactivation Due To Calcium Entry Defect 1 Combined Immunodeficiency Due To Orai1 Deficiency IMD9 Cid Due To Orai1 Deficiency Severe Combined Immunodeficiency Due To Crac Channel Dysfunction Immunodeficiency, Type 9
Developmental And Epileptic Encephalopathy 25	Developmental And Epileptic Encephalopathy, 25 Dee25 Developmental And Epileptic Encephalopathy 25, With Amelogenesis Imperfecta Early Infantile Epileptic Encephalopathy 25 Encephalopathy, Epileptic, Early Infantile, Type 25
Heimler Syndrome 1	Deafness Enamel Hypoplasia Nail Defects Heimler Syndrome HMLR1 Hearing Loss, Sensorineural, With Enamel Hypoplasia And Nail Defects Peroxisome Biogenesis Disorder 1c Pbd1c Deafness-Enamel Hypoplasia-Nail Defects Syndrome Sensorineural Hearing Loss, Enamel Hypoplasia, And Nail Abnormalities Peroxisomal Biogenesis Disorder 1c Bilateral Sensorineural Hearing Loss, Enamel Hypoplasia And Nail Defects Hearing Loss-Enamel Hypoplasia-Nail Defects Syndrome Heimler, Syndrome Heimler Syndrome, Type 1
Amelogenesis Imperfecta, Hypomaturation Type, Iia5	Amelogenesis Imperfecta Hypomaturation Type 2a5 AI2A5 Amelogenesis Imperfecta, Type Iia5 Amelogenesis Imperfecta Hypomaturation Type Iia5 Amelogenesis Imperfecta Type Iia5 Amelogenesis Imperfecta, Hypomaturation Type, 2a5
Amelogenesis Imperfecta	Ai Congenital Enamel Hypoplasia Al - [Amelogenesis Imperfecta]
Osteogenesis Imperfecta, Type V	Osteogenesis Imperfecta Type 5 OI5 Osteogenesis Imperfecta Type V Oi Type 5 Oi Type V Oi, Type V Oi With Calcification In Interosseous Membranes Type V Oi Osteogenesis Imperfecta 5 Oi-V
Spondyloepimetaphyseal Dysplasia With Joint Laxity	Dysplasia, Spondyloepimetaphyseal, With Joint Laxity Semdjl Spondyloepimetaphyseal Dysplasia Joint Laxity Semd-Jl Semdjl1 Spondyloepimetaphyseal Dysplasia With Joint Laxity Type 1 Spondyloepimetaphyseal Dysplasia With Joint Laxity, Beighton Type
Alacrima, Achalasia, And Mental Retardation Syndrome	AAMR Alacrima, Achalasia, And Intellectual Disability Syndrome Alacrima, Achalasia, And Impaired Intellectual Development Syndrome Intellectual Disability
Immunodeficiency 10	Immune Dysfunction With T-Cell Inactivation Due To Calcium Entry Defect 2 Combined Immunodeficiency Due To Stim1 Deficiency IMD10 Stim1 Deficiency Cid Due To Stim1 Deficiency Immune Dysfunction, With T-Cell Inactivation Due To Calcium Entry Defect 2 Immunodeficiency, Type 10
T Cell And Nk Cell Immunodeficiency
Teeth Hard Tissue Disease
Early Infantile Epileptic Encephalopathy	Early Infantile Epileptic Encephalopathy With Burst-Suppression Early Infantile Epileptic Encephalopathy With Suppression Bursts Eiee Early Infantile Epileptic Encephalopathy With Suppression-Bursts Ohtahara Syndrome Encephalopathy, Epileptic, Early Infantile

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12120	ROGDI Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ROGDI	VGNC	VGNC:45689
Bos taurus	ROGDI	VGNC	VGNC:34083
Felis catus	ROGDI	VGNC	VGNC:64716
Rattus norvegicus	ROGDI	RGD	RGD:1560021
Mus musculus	ROGDI	MGD	MGI:1913299
Macaca mulatta	ROGDI	VGNC	VGNC:76862
Others	ROGDI	NCBI