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79843

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By Targets:	Autophagy (1) Dopamine Receptor (1) GABA Receptor (2) MicroRNA (8) Na+/Ca2+ Exchanger (2)
By Research Areas:	Cancer (9) Cardiovascular Disease (1) Neurological Disease (3)
Oligonucleotides:	miRNA mimics (2) miRNA agomirs (2) miRNA antagomirs (2) MicroRNAs (8) miRNA inhibitors (2)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15415

KB-R7943 mesylate 4 Publications Verification	Na+/Ca2+ Exchanger Autophagy	Cancer
KB-R7943 mesylate is a widely used inhibitor of the reverse Na ⁺/Ca ²⁺ exchanger (NCX_rev) with IC₅₀ of 5.7±2.1 μM. KB-R7943 mesylate induces cancer cell death via activating the JNK pathway and blocking autophagic flux.

HY-A0151

Thioproperazine 2 Publications Verification RP 7843; SKF 5883; Thioperazine	Dopamine Receptor	Neurological Disease
Thioproperazine (RP 7843) is an orally active antipsychotic agent with calming, antiemetic activity. Thioproperazine is effective in promoting the release of dopamine in rat striatum. Thioproperazine can be used in studies of schizophrenia and bipolar disorder .

HY-129431

*U-89843A* PNU-89843	GABA Receptor	Neurological Disease
U-89843A (PNU-89843) is a GABAA receptors positive allosteric modulator (PAM). U-89843A enhances GABA-induced Cl ^- currents in the α1β2γ2, α3β2γ2 and α6β2γ2 subtypes. U-89843A shows antioxidant and sedative effects .

HY-103497

*U-89843A hydrochloride* PNU-89843 hydrochloride	GABA Receptor	Neurological Disease
U-89843A (PNU-89843) hydrochloride is a GABAA receptors positive allosteric modulator (PAM). U-89843A hydrochloride enhances GABA-induced Cl ^- currents in the α1β2γ2, α3β2γ2 and α6β2γ2 subtypes. U-89843A hydrochloride shows antioxidant and sedative effects .

HY-138947

KB-R7943	Na+/Ca2+ Exchanger	Cardiovascular Disease
KB-R7943 (compound 1) is an inhibitor of sodium-calcium exchanger with an IC₅₀ value of 5.1 μM. KB-R7943 can be used as a tool in heart and renal failure models .

HY-RI02423A

*hsa-miR-7843-5p antagomir*	MicroRNA	Cancer
hsa-miR-7843-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-7843-5p antagomir hsa-miR-7843-5p antagomir

HY-R02423

*hsa-miR-7843-5p mimic*	MicroRNA	Cancer
hsa-miR-7843-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-7843-5p mimic hsa-miR-7843-5p mimic

HY-R02422

*hsa-miR-7843-3p mimic*	MicroRNA	Cancer
hsa-miR-7843-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-7843-3p mimic hsa-miR-7843-3p mimic

HY-RI02422

*hsa-miR-7843-3p inhibitor*	MicroRNA	Cancer
hsa-miR-7843-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-7843-3p inhibitor hsa-miR-7843-3p inhibitor

HY-RI02423

*hsa-miR-7843-5p inhibitor*	MicroRNA	Cancer
hsa-miR-7843-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-7843-5p inhibitor hsa-miR-7843-5p inhibitor

HY-RI02422A

*hsa-miR-7843-3p antagomir*	MicroRNA	Cancer
hsa-miR-7843-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-7843-3p antagomir hsa-miR-7843-3p antagomir

HY-R02423A

*hsa-miR-7843-5p agomir*	MicroRNA	Cancer
hsa-miR-7843-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-7843-5p agomir hsa-miR-7843-5p agomir

HY-R02422A

*hsa-miR-7843-3p agomir*	MicroRNA	Cancer
hsa-miR-7843-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-7843-3p agomir hsa-miR-7843-3p agomir

Host:	Mouse (8) Rabbit (1)
Reactivity:	Human (9) Rat (3) Mouse (3) Dog (2)
Application:	IHC-P (6) ICC/IF (4) WB (3) FC (2)
Isotype:	IgG (1) IgG1 (4) IgG2a (4)
Conjugation:	Non-conjugated (9)
Clonality:	Monoclonal (4)
Modification:	Phosphorylated (1) Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88259

	USP36 Antibody (YA7943) DUB1	IHC-P, ICC/IF	Human, Dog
	USP36 Antibody (YA7943) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to USP36.

HY-P88259A

	USP36 Antibody (YA7943)(PBS only) DUB1	IHC-P, ICC/IF	Human, Dog
	USP36 Antibody (YA7943) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to USP36.

HY-P88159

	PKLR Antibody (YA7843) PK1; PKL; PKR; PKRL; RPK	WB, ICC/IF, FC	Human
	PKLR Antibody (YA7843) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PKLR.

HY-P88159A

	PKLR Antibody (YA7843)(PBS only) PK1; PKL; PKR; PKRL; RPK	WB, ICC/IF, FC	Human, Mouse, Rat
	PKLR Antibody (YA7843) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PKLR.

HY-P88299

	LAMB3 Antibody (YA7983) AI1A; BM600-125KDA; LAM5; LAMNB1	IHC-P	Human
	LAMB3 Antibody (YA7983) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to LAMB3.

HY-P88300

	RBFOX1 Antibody (YA7984) 2BP1; A2BP1; FOX-1; FOX1; HRNBP1	IHC-P	Human, Mouse, Rat
	RBFOX1 Antibody (YA7984) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RBFOX1.

HY-P88299A

	LAMB3 Antibody (YA7983)(PBS only) AI1A; BM600-125KDA; LAM5; LAMNB1	IHC-P	Human
	LAMB3 Antibody (YA7983) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to LAMB3.

HY-P88300A

	RBFOX1 Antibody (YA7984)(PBS only) 2BP1; A2BP1; FOX-1; FOX1; HRNBP1	IHC-P	Human, Mouse, Rat
	RBFOX1 Antibody (YA7984) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RBFOX1.

HY-P810579

	Phospho-BCAR1 (Tyr410) Antibody (YA9843) BCAR 1; CAS; CAS1; Cass1; CRKAS; p130cas	WB	Human
	Phospho-BCAR1 (Tyr410) Antibody (YA9843) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-BCAR1 (Tyr410).

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Cat. No.	Product Name		Classification

HY-RI02423A

*hsa-miR-7843-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-7843-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R02423

*hsa-miR-7843-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-7843-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R02422

*hsa-miR-7843-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-7843-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI02422

*hsa-miR-7843-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-7843-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI02423

*hsa-miR-7843-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-7843-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI02422A

*hsa-miR-7843-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-7843-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R02423A

*hsa-miR-7843-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-7843-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R02422A

*hsa-miR-7843-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-7843-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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