SPX - spexin hormone Gene

Homo sapiens

Also known as C12orf39

Gene ID: 80763 | Gene type: protein coding

About SPX

Cytogenetic location: 12p12.1 Genomic coordinates (GRCh38): 12:21,526,296-21,532,947 (from NCBI)

This gene has 8 transcripts (splice variants) and 180 orthologues. Biased expression in fat (RPKM 72.3), thyroid (RPKM 9.5) and 4 other tissues.

Summary

The protein encoded by this gene is a hormone involved in modulation of cardiovascular and renal function. It has also been shown in rats to cause weight loss. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]

SPX Products(1)

mRNA	Protein	Name
NM_030572.4	NP_085049.1	spexin precursor

SPX Protein Structure

Spexin

0
100
116 a.a.

Protein Preferred Names

Protein Names

spexin

NPQ

Related Diseases

Diseases

Alias

Noonan Syndrome 9

NS9	Noonan Syndrome, Type 9

Acute Endophthalmitis

Bjornstad Syndrome

BJS	Pili Torti And Nerve Deafness
Ptd	Pili Torti-Deafness Syndrome
Deafness-Pili Torti-Hypogonadism Syndrome	Deafness And Pili Torti, Bjornstad Type
Pili Torti-Sensorineural Hearing Loss	Björnstad Syndrome
Ptnd	Hearing Loss-Pili Torti-Hypogonadism Syndrome
Bjoernstad Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P5931	Spinoxin	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13741	SPX Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SPX	VGNC	VGNC:100108
Canis familiaris	SPX	VGNC	VGNC:46784
Mus musculus	SPX	MGD	MGI:2442262
Felis catus	SPX	VGNC	VGNC:65667
Rattus norvegicus	SPX	RGD	RGD:1587448
Bos taurus	SPX	VGNC	VGNC:35262

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