PRRT1 - proline rich transmembrane protein 1 Gene

Homo sapiens

Also known as NG5; DSPD1; C6orf31; IFITMD7; SynDIG4

Gene ID: 80863 | Gene type: protein coding

About PRRT1

Cytogenetic location: 6p21.32 Genomic coordinates (GRCh38): 6:32,148,363-32,153,083 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 130 orthologues and 4 paralogues. Biased expression in brain (RPKM 24.0), ovary (RPKM 12.1) and 6 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in several processes, including long-term synaptic depression; protein localization to cell surface; and regulation of AMPA receptor activity. Predicted to act upstream of or within several processes, including learning or memory; long-term synaptic potentiation; and synapse organization. Predicted to be located in postsynaptic density membrane and synaptic vesicle membrane. Predicted to be active in glutamatergic synapse and membrane. Predicted to be integral component of postsynaptic membrane. [provided by Alliance of Genome Resources, Apr 2022]

PRRT1 Products(2)

mRNA	Protein	Name
NM_001363780.2	NP_001350709.1	proline-rich transmembrane protein 1 isoform 2
NM_030651.4	NP_085154.3	proline-rich transmembrane protein 1 isoform 1

PRRT1 Protein Structure

CD225

0
100
200
306 a.a.

Protein Preferred Names

Protein Names

proline-rich transmembrane protein 1

dispanin subfamily D member 1

Related Diseases

Diseases

Alias

Alzheimer Disease 8

Ad8	Alzheimer'S Disease 8
Alzheimer Disease, Familial, 8	Alzheimer Disease, Familial 8
Alzheimer'S Disease 8, Late Onset

Osteogenesis Imperfecta, Type V

Osteogenesis Imperfecta Type 5	OI5
Osteogenesis Imperfecta Type V	Oi Type 5
Oi Type V	Oi, Type V
Oi With Calcification In Interosseous Membranes	Type V Oi
Osteogenesis Imperfecta 5	Oi-V

Delayed Sleep Phase Disorder

Delayed Sleep Phase Syndrome	Delayed Sleep Phase Syndrome, Susceptibility To
DSPD	Delayed Sleep Phase Disorder, Susceptibility To
DSPS	Sleep Phase, Delayed, Disorder
Sleep Phase Syndrome, Delayed, Susceptibility To

Episodic Kinesigenic Dyskinesia 1

Paroxysmal Kinesigenic Choreoathetosis	Paroxysmal Kinesigenic Dyskinesia
Dystonia 10	Familial Paroxysmal Kinesigenic Dyskinesia
Episodic Kinesigenic Dyskinesia	EKD1
Pkc	Pkd
Dyt10	Familial Pkd
Paroxysmal Kinesigenic Choreathetosis	Familial Paroxysmal Dystonia
Dystonia, Familial Paroxysmal	Dyt-Prrt2
Dystonia, Type 10

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11241	PRRT1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PRRT1	VGNC	VGNC:83449
Canis familiaris	PRRT1	VGNC	VGNC:49684
Felis catus	PRRT1	VGNC	VGNC:102497
Bos taurus	PRRT1	VGNC	VGNC:50003
Mus musculus	PRRT1	MGD	MGI:1932118
Rattus norvegicus	PRRT1	RGD	RGD:1359348

Name
Email *

	Sorry, but the email address you supplied was invalid.