LRRC14 - leucine rich repeat containing 14 Gene

Also Known as LRRC14A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9684

Summary

This gene encodes a leucine-rich repeat-containing protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Ubiquitous expression in prostate (RPKM 7.1), brain (RPKM 5.8) and 25 other tissues.

LRRC14 Products (1)

mRNA Protein Name
NG_033083.2 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables kinase binding IPI
IPI: Inferred from physical interaction
27426725 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
21145461 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of NF-kappaB transcription factor activity IDA
IDA: Inferred from direct assay
27426725 GOA
involved in negative regulation of toll-like receptor signaling pathway IDA
IDA: Inferred from direct assay
27426725 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
27426725 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LRRC14 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
LRRC14 Q15048 CUL2 Homo sapiens Q13617
Anti Tag CoIP
21145461
Intra
LRRC14 Q15048 CUL2 Homo sapiens Q13617
TAP
21145461
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07808 LRRC15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17927 Lrrc15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07806 LRRC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07807 LRRC10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07809 LRRC17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07818 LRRC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07819 LRRC41 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18668 Lrrc4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20442 Lrrc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24397 Lrrc15 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25154 Lrrc4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26951 Lrrc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown