2. Metabolic Enzyme/Protease
  3. HMG-CoA Reductase (HMGCR)
  4. HMG-CoA Reductase-IN-1

HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor. HMG-CoA Reductase-IN-1has high HMGR inhibitory activity and OATP1B1 affinity with pIC50 and pKm values of 8.54 and 1.98, respectively. HMG-CoA Reductase-IN-1 can be used for the research of hypercholesterolemia.

For research use only. We do not sell to patients.

HMG-CoA Reductase-IN-1 Chemical Structure

HMG-CoA Reductase-IN-1 Chemical Structure

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HMG-CoA Reductase-IN-1 Related Antibodies

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Description

HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor. HMG-CoA Reductase-IN-1has high HMGR inhibitory activity and OATP1B1 affinity with pIC50 and pKm values of 8.54 and 1.98, respectively. HMG-CoA Reductase-IN-1 can be used for the research of hypercholesterolemia[1].

IC50 & Target

pIC50: 8.54 (HMGR); pKm: 1.98 (OATP1B1)[1]
Molecular Weight

507.54

Formula

C27H29N3O7
SMILES

OC1=CC=C(C=C1)NC(C2=C(/C=C/[C@H](C[C@@H](O)CC(O)=O)O)C(C(C)C)=NC(C3=CC=C(C=C3)O)=N2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HMG-CoA Reductase-IN-1 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HMG-CoA Reductase-IN-1HMG-CoA Reductase (HMGCR)organic anion transporting polypeptide 1B1 (OATP1B1)hypercholesterolemiaHMGRHMG-CoAInhibitorinhibitorinhibit

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