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Cat. No.: HY-179323

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RIPK1-IN-36

RIPK1-IN-36 (Example 4.1) is a RIPK1 inhibitor with an EC₅₀ of <25 nM. RIPK1-IN-36 can be used for the study of RIPK1-related diseases.

For research use only. We do not sell to patients.

CAS No.: 2924736-22-9
Formula: C₂₂H₂₂FN₅O₂
Molecular Weight:407.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

RIPK1-IN-36 Chemical Structure

CAS No.: 2924736-22-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

RIPK1-IN-36 (Example 4.1) is a RIPK1 inhibitor with an EC₅₀ of <25 nM. RIPK1-IN-36 can be used for the study of RIPK1-related diseases^[1].

IC₅₀ & Target^[1]

RIPK1

<25 nM (EC₅₀)

All RIP kinase Isoforms :

Chemical Information

CAS No. 2924736-22-9
Molecular Weight 407.44
Formula C₂₂H₂₂FN₅O₂
SMILES

O=C1C2(CCN(C(N3N=C4)=CC=NC3=C4F)CC2)O[C@@]5([H])N1[C@H](C6=CC=CC=C6)CC5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Abdelghani Abe Achab, et al. Spirotricycle ripk1 inhibitors and methods of uses thereof. WO2023076218A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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RIPK1-IN-36

All RIP kinase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

RIPK1-IN-36 Related Classifications

HY-179323 Related Classifications