Cdkl3 - cyclin-dependent kinase-like 3 Gene

Also Known as B230379H01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 213084

Summary

Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within dendrite extension; negative regulation of axon extension; and positive regulation of dendrite morphogenesis. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human CDKL3 (cyclin dependent kinase like 3). [provided by Alliance of Genome Resources, Apr 2022]

Cdkl3 Products (7)

mRNA Protein Name
NM_001166653.1 NP_001160125.1 cyclin-dependent kinase-like 3 isoform 1
NM_001166654.1 NP_001160126.1 cyclin-dependent kinase-like 3 isoform 3
NM_001166655.1 NP_001160127.1 cyclin-dependent kinase-like 3 isoform 4
NM_001166656.1 NP_001160128.1 cyclin-dependent kinase-like 3 isoform 5
NM_001166657.1 NP_001160129.1 cyclin-dependent kinase-like 3 isoform 6
NM_001363476.1 NP_001350405.1 cyclin-dependent kinase-like 3 isoform 4
NM_153785.4 NP_722480.3 cyclin-dependent kinase-like 3 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within dendrite extension IMP
IMP: Inferred from mutant phenotype
20347982 MGI
acts upstream of or within negative regulation of axon extension IMP
IMP: Inferred from mutant phenotype
20347982 MGI
acts upstream of or within positive regulation of dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
20347982 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclin-dependent kinase-like 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-161847 HZ1 Inhibitor 99.20% Unkown
HY-RS02407 CDKL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21518 Cdkl3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28036 Cdkl3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdkl3 NCBI NCBI:51265