Junb - JunB proto-oncogene, AP-1 transcription factor subunit Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24517

Summary

Enables DNA-binding transcription factor activity; double-stranded DNA binding activity; and sequence-specific DNA binding activity. Involved in several processes, including response to cAMP; response to steroid hormone; and transcription by RNA polymerase II. Located in nucleus. Biomarker of renal carcinoma. Orthologous to human JUNB (JunB proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Junb Products (1)

mRNA Protein Name
NM_021836.2 NP_068608.2 transcription factor JunB

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12371906 RGD
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
10830307 RGD
enables double-stranded DNA binding IDA
IDA: Inferred from direct assay
10830307 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10830307 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to hormone stimulus IEP
IEP: Inferred from expression pattern
11460264 RGD
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
8593588 RGD
involved in female pregnancy IEP
IEP: Inferred from expression pattern
12080023 RGD
involved in response to 4-nitroquinoline N-oxide IEP
IEP: Inferred from expression pattern
14674993 RGD
involved in response to cAMP IEP
IEP: Inferred from expression pattern
18280640 RGD
involved in response to corticosterone IEP
IEP: Inferred from expression pattern
18485334 RGD
involved in response to cytokine IEP
IEP: Inferred from expression pattern
18280640 RGD
involved in response to light stimulus IEP
IEP: Inferred from expression pattern
11146118 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
15126239 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
10934195 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
10934195 RGD
involved in response to progesterone IEP
IEP: Inferred from expression pattern
12080023 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
12093589 RGD
involved in transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
10830307 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Junb Protein Structure

Jun

Jun: pfam03957 (5 - 252)

bZIP_Jun

bZIP_Jun: cd14696 (266 - 325)

bZIP_Jun

bZIP_Jun: cd14696 (267 - 318)

  • 0
  • 100
  • 200
  • 300
  • 344 a.a.
Protein Preferred Names Protein Names

transcription factor JunB

  • Jun-B oncogene

  • jun B proto-oncogene

  • transcription factor AP-1 subunit JunB

  • transcription factor jun-B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W011927 4,4'-Sulfonyldiphenol 99.81% Unkown
HY-W011927S 4,4'-Sulfonyldiphenol-d8 99.21% Unkown
HY-RS07058 Junb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07057 JUNB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07059 Junb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12025 RNASEH2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W092110 Phe-Tyr Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Junb NCBI NCBI:3726