Phe-Tyr
Based on 1 Customer Validation
Phe-Tyr is an ACE inhibitor. Phe-Tyr can be isolated from wakame. Phe-Tyr exhibits mild concentration-dependent toxicity to fibroblasts. Phe-Tyr can be used in studies related to hypertension and cardiovascular diseases.
For research use only. We do not sell to patients.
- CAS No.: 17355-18-9
- Formula: C18H20N2O4
- Molecular Weight:328.36
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO | Inhibition |
68.5985 %
Compound: PHENYLALANYLTYROSINE
|
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
|
[PMID: 23571415] |
| CHO | Inhibition |
78.5874 %
Compound: PHENYLALANYLTYROSINE
|
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
|
[PMID: 23571415] |
Phe-Tyr (24 h) shows slight cytotoxicity to L929 fibroblast cells, while encapsulation in PLGA nanoparticles eliminates this toxic effect[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 17355-18-9
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Appearance Solid
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Molecular Weight 328.36
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Formula C18H20N2O4
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Sequence
Phe-Tyr
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Sequence Shortening
FY
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)