Lgmn - legumain Gene

Also Known as Prsc1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 63865

Summary

Enables cysteine-type endopeptidase activity. Predicted to be involved in several processes, including learning or memory; positive regulation of chemotaxis; and proteolysis. Predicted to act upstream of or within negative regulation of neuron apoptotic process; regulation of growth; and response to acidic pH. Located in lysosome. Orthologous to human LGMN (Legumain). [provided by Alliance of Genome Resources, Apr 2022]

Lgmn Products (1)

mRNA Protein Name
NM_022226.3 NP_071562.3 legumain precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cysteine-type endopeptidase activity IMP
IMP: Inferred from mutant phenotype
9065484 RGD
Cellular Component GO Annotation Evidence References Source
located in lysosome IDA
IDA: Inferred from direct assay
9742219 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

legumain

  • asparaginyl endopeptidase

  • protease, cysteine 1

  • protease, cysteine, 1 (legumain)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07617 LGMN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17268 Lgmn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23722 Lgmn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lgmn NCBI NCBI:5641