Frenlosirsen sodium
Based on 1 Customer Validation
Frenlosirsen sodium (ION-935918 sodium; ION251 sodium) is an antisense oligonucleotide and also an IRF4 inhibitor. Frenlosirsen sodium inhibits the survival of malignant plasma cells, reduces the burden of myeloma progenitor cells and prevents disease recurrence. Frenlosirsen sodium is applicable to myeloma-related research.
For research use only. We do not sell to patients.
- Purity: 96.46%
- CAS No.: 2304711-82-6
- Formula: C177H211N63Na15O89P15S15
- Molecular Weight:5935.36
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Frenlosirsen (28-day dosing cycle, intravenous infusion, maximum dose of 660 mg) sodium shows no dose-limiting toxicity and only mild drug-related adverse events in a Phase 1a clinical study of relapsed/refractory multiple myeloma[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2304711-82-6
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Appearance Solid
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Molecular Weight 5935.36
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Formula C177H211N63Na15O89P15S15
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Color White to off-white
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SMILES
[Frenlosirsen (sodium)]
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Synonyms
ION-935918 sodium; ION251 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2242 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)