NHS ester
Based on 1 publication(s) in Google Scholar
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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- 純度: 95.0%
- CAS 番号: 117235-10-6
- 分子式: C7H9NO4S
- 分子量:203.22
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 3-Mercaptopropionic acid NHS ester
MorePROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 117235-10-6
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性状 Liquid (Density: 1.40±0.1 g/cm3)
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分子量 203.22
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分子式 C7H9NO4S
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Color Colorless to light yellow
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SMILES
O=C(ON1C(CCC1=O)=O)CCS
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別名
3-Mercaptopropionic acid NHS ester
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
Spatiotemporal Dynamic Immunomodulation by Infection-Mimicking Gels Enhances Broad and Durable Protective Immunity Against Heterologous Viruses. [Abstract]2025 Jan 13:e2412116. PMID: 39804984
溶剤 & 溶解度
DMSO : 100 mg/mL (492.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (466 KB)
- English - EN (466 KB)
- Français - FR (466 KB)
- Deutsch - DE (466 KB)
- Norwegian - NO (466 KB)
- Español - ES (466 KB)
- Swedish - SV (466 KB)
- Italian - IT (466 KB)
- Korean - KR (466 KB)
- Portuguese - PT (466 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9208 mL | 24.6039 mL | 49.2078 mL | 123.0194 mL |
| 5 mM | 0.9842 mL | 4.9208 mL | 9.8416 mL | 24.6039 mL | |
| 10 mM | 0.4921 mL | 2.4604 mL | 4.9208 mL | 12.3019 mL | |
| 15 mM | 0.3281 mL | 1.6403 mL | 3.2805 mL | 8.2013 mL | |
| 20 mM | 0.2460 mL | 1.2302 mL | 2.4604 mL | 6.1510 mL | |
| 25 mM | 0.1968 mL | 0.9842 mL | 1.9683 mL | 4.9208 mL | |
| 30 mM | 0.1640 mL | 0.8201 mL | 1.6403 mL | 4.1006 mL | |
| 40 mM | 0.1230 mL | 0.6151 mL | 1.2302 mL | 3.0755 mL | |
| 50 mM | 0.0984 mL | 0.4921 mL | 0.9842 mL | 2.4604 mL | |
| 60 mM | 0.0820 mL | 0.4101 mL | 0.8201 mL | 2.0503 mL | |
| 80 mM | 0.0615 mL | 0.3075 mL | 0.6151 mL | 1.5377 mL | |
| 100 mM | 0.0492 mL | 0.2460 mL | 0.4921 mL | 1.2302 mL |
3-Mercaptopropionic acid NHS ester 関連分類
HY-136159 関連分類
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