ALDH2 activator 1
Based on 1 Customer Validation
ALDH2 activator 1 (Compound Z17) is an allosteric aldehyde dehydrogenase 2 (ALDH2) agonist. ALDH2 activator 1 enhances cardiac function and reduces myocardial necrosis in a mouse model of myocardial ischemia-reperfusion. ALDH2 activator 1 is promising for research of cardiovascular diseases such as myocardial infarction (MI).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.88%
- CAS 番号: 2988020-77-3
- 分子式: C21H20ClFN4O3
- 分子量:430.86
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
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ALDH2 |
化学情報
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CAS 番号 2988020-77-3
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性状 Solid
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分子量 430.86
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分子式 C21H20ClFN4O3
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Color White to off-white
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SMILES
O=C(NCC1=CC=C(OC)C(F)=C1)C2=C(OCC3CC3)C=CC(N4C=NN=C4)=C2Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (232.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3209 mL | 11.6047 mL | 23.2094 mL | 58.0235 mL |
| 5 mM | 0.4642 mL | 2.3209 mL | 4.6419 mL | 11.6047 mL | |
| 10 mM | 0.2321 mL | 1.1605 mL | 2.3209 mL | 5.8023 mL | |
| 15 mM | 0.1547 mL | 0.7736 mL | 1.5473 mL | 3.8682 mL | |
| 20 mM | 0.1160 mL | 0.5802 mL | 1.1605 mL | 2.9012 mL | |
| 25 mM | 0.0928 mL | 0.4642 mL | 0.9284 mL | 2.3209 mL | |
| 30 mM | 0.0774 mL | 0.3868 mL | 0.7736 mL | 1.9341 mL | |
| 40 mM | 0.0580 mL | 0.2901 mL | 0.5802 mL | 1.4506 mL | |
| 50 mM | 0.0464 mL | 0.2321 mL | 0.4642 mL | 1.1605 mL | |
| 60 mM | 0.0387 mL | 0.1934 mL | 0.3868 mL | 0.9671 mL | |
| 80 mM | 0.0290 mL | 0.1451 mL | 0.2901 mL | 0.7253 mL | |
| 100 mM | 0.0232 mL | 0.1160 mL | 0.2321 mL | 0.5802 mL |