AZ-GHS-22
AZ-GHS-22 is a potent, non-CNS penetrant GHS-R1a inverse agonist (IC50=0.77 nM).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1143020-91-0
- 分子式: C27H33ClN6O5S2
- 分子量:621.17
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
0.77 nM
Compound: 22
|
Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
|
[PMID: 24967667] |
| HEK293 | IC50 |
1.1 nM
Compound: 22
|
Displacement of [125I]human ghrelin from mouse GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
Displacement of [125I]human ghrelin from mouse GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
|
[PMID: 24967667] |
| HEK293 | IC50 |
3.4 nM
Compound: 22
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Displacement of [125I]human ghrelin from rat GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
Displacement of [125I]human ghrelin from rat GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
|
[PMID: 24967667] |
化学情報
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CAS 番号 1143020-91-0
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分子量 621.17
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分子式 C27H33ClN6O5S2
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SMILES
O=C(NC(NC1=NC2=CC=C(S(=O)(CCCN3CCN(C)CC3)=O)C=C2S1)=O)C4=CC(N5CCOCC5)=CC=C4Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
AZ-GHS-22 関連分類
HY-137061 関連分類
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