Biotin-H10
Based on 1 publication(s) in Google Scholar
Biotin-H10 is a specific anterior gradient homolog 2 (AGR2) inhibitor with a KD of 6.4 nM. Biotin-H10 inhibits cancer cells viability.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.94%
- 分子式: C79H132N22O21S3
- 分子量:1822.22
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保管条件:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
MedChemExpress(MCE)の使用を引用している文献 Biotin-H10
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生物活性
KD: 6.4 nM (AGR2)[1]
化学情報
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性状 Solid
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分子量 1822.22
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分子式 C79H132N22O21S3
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Color White to off-white
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配列
{Biotin}-Gly-Gly-Gly-Ser-Gly-Met-Lys-Met-Gln-Val-Arg-Ile-Tyr-Leu-Val
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シーケンスの短縮
{Biotin}-GGGSGMKMQVRIYLV
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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FASEB J
Tumor-Associated Neutrophils Secrete AGR2 to Promote Colorectal Cancer Progression by Stabilizing ALYREF to Boost Snail m5C Modification. [Abstract]2026 Jun 15;40(11):e71968. PMID: 42241033
溶剤 & 溶解度
DMSO : 50 mg/mL (27.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5488 mL | 2.7439 mL | 5.4878 mL | 13.7195 mL |
| 5 mM | 0.1098 mL | 0.5488 mL | 1.0976 mL | 2.7439 mL | |
| 10 mM | 0.0549 mL | 0.2744 mL | 0.5488 mL | 1.3720 mL | |
| 15 mM | 0.0366 mL | 0.1829 mL | 0.3659 mL | 0.9146 mL | |
| 20 mM | 0.0274 mL | 0.1372 mL | 0.2744 mL | 0.6860 mL | |
| 25 mM | 0.0220 mL | 0.1098 mL | 0.2195 mL | 0.5488 mL |