Bromo-PEG2-C2-Boc
Based on 1 Customer Validation
Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.0%
- CAS 番号: 1381861-91-1
- 分子式: C11H21BrO4
- 分子量:297.19
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1381861-91-1
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性状 Liquid (Density: 1.240±0.06 g/cm3)
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分子量 297.19
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分子式 C11H21BrO4
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCOCCBr
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (336.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (393 KB)
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- Deutsch - DE (393 KB)
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- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3649 mL | 16.8243 mL | 33.6485 mL | 84.1213 mL |
| 5 mM | 0.6730 mL | 3.3649 mL | 6.7297 mL | 16.8243 mL | |
| 10 mM | 0.3365 mL | 1.6824 mL | 3.3649 mL | 8.4121 mL | |
| 15 mM | 0.2243 mL | 1.1216 mL | 2.2432 mL | 5.6081 mL | |
| 20 mM | 0.1682 mL | 0.8412 mL | 1.6824 mL | 4.2061 mL | |
| 25 mM | 0.1346 mL | 0.6730 mL | 1.3459 mL | 3.3649 mL | |
| 30 mM | 0.1122 mL | 0.5608 mL | 1.1216 mL | 2.8040 mL | |
| 40 mM | 0.0841 mL | 0.4206 mL | 0.8412 mL | 2.1030 mL | |
| 50 mM | 0.0673 mL | 0.3365 mL | 0.6730 mL | 1.6824 mL | |
| 60 mM | 0.0561 mL | 0.2804 mL | 0.5608 mL | 1.4020 mL | |
| 80 mM | 0.0421 mL | 0.2103 mL | 0.4206 mL | 1.0515 mL | |
| 100 mM | 0.0336 mL | 0.1682 mL | 0.3365 mL | 0.8412 mL |