Clindamycin 2,4-diphosphate
Clindamycin 2,4-diphosphate is a related impurity of Clindamycin phosphate (HY-B1064), a prodrug of Clindamycin (HY-B1455). Clindamycin phosphate inhibits protein synthesis by targeting the bacterial ribosomal 50S subunit.
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- CAS 番号: 1309048-48-3
- 分子式: C18H35ClN2O11P2S
- 分子量:584.94
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
After entering the body, Clindamycin phosphate is rapidly converted into its active form, clindamycin, which effectively inhibits anaerobic bacteria (such as Bacteroides fragilis) and Gram-positive bacteria (such as Staphylococcus aureus and Streptococcus species), but has weaker effects against most Gram-negative bacteria[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1309048-48-3
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分子量 584.94
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分子式 C18H35ClN2O11P2S
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SMILES
O=C([C@@H]1C[C@H](CN1C)CCC)N[C@@H]([C@]2([H])[C@@H]([C@@H]([C@H]([C@H](O2)SC)OP(O)(O)=O)O)OP(O)(O)=O)[C@@H](Cl)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Li Y, et al. [Isolation and identification of impurities from raw material of clindamycin phosphate]. Yao Xue Xue Bao. 2010 Nov;45(11):1415-20. Chinese. [Content Brief]
[2]. Li H, et al. Clindamycin hydrochloride and clindamycin phosphate: two drugs or one? A retrospective analysis of a spontaneous reporting system. Eur J Clin Pharmacol. 2017 Feb;73(2):251-253. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Clindamycin 2,4-diphosphate 関連分類
HY-163967 関連分類
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