CLX-0921
CLX-0921 is an orally active PPARγ agonist with an IC50 of 1.54 μM. CLX-0921 has a potent antihyperglycemic activity, and can be used for the study of type 2 diabetes.
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- CAS 番号: 249886-47-3
- 分子式: C28H25NO7S
- 分子量:519.57
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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PPARγ 1.54 μM (IC50) |
CLX-0921 (0.01 M, 0.1 M, 1.0 M, and 10 M) increases glucose uptake in 3T3-L1 adipocytes. CLX-0921 has potent antihyperglycemic activity with low adipogenic potential[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male C57BL/KsJ-db/db and C57BL/6J-ob/ob mice (7-week-old)[1]
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Dosage:3.1 mg/kg, 6.3 mg/kg, and 12.5 mg/kg
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Administration:Oral gavage; once daily; for 19 days
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Result:Showed dose-dependent antihyperglycemic activity.
化学情報
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CAS 番号 249886-47-3
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分子量 519.57
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分子式 C28H25NO7S
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SMILES
O=C(OC)/C(C1=CC=C(OC2=CC=C(CC(SC(N3)=O)C3=O)C=C2)C=C1)=C/C4=CC(OC)=CC(OC)=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CLX-0921 関連分類
HY-19394 関連分類
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